Unfolded Protein Response Differentially Modulates the Platelet Phenotype.

Jain, Kanika; Tyagi, Tarun; Du, Jing; Hu, Xiaoyue; Patell, Kanchi; Martin, Kathleen A; Hwa, John

Jain, Kanika; Tyagi, Tarun; Du, Jing; Hu, Xiaoyue; Patell, Kanchi; Martin, Kathleen A; Hwa, John.

Afiliação

Jain K; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
Tyagi T; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
Du J; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
Hu X; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
Patell K; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
Martin KA; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
Hwa J; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.

Circ Res ; 131(4): 290-307, 2022 08 05.

Article em En | MEDLINE | ID: mdl-35862006

Assuntos

Doenças Cardiovasculares; Endorribonucleases; Fator 6 Ativador da Transcrição/genética; Fator 6 Ativador da Transcrição/metabolismo; Animais; Proteínas Quinases Dependentes de AMP Cíclico/metabolismo; Estresse do Retículo Endoplasmático; Endorribonucleases/genética; Endorribonucleases/metabolismo; Humanos; Camundongos; Fenótipo; Proteínas Serina-Treonina Quinases/genética; Resposta a Proteínas não Dobradas; Proteína 1 de Ligação a X-Box/genética; Proteína 1 de Ligação a X-Box/metabolismo; eIF-2 Quinase

Palavras-chave

blood platelets; diabetes mellitus; endoplasmic reticulum stress; platelet activation; protein aggregates; unfolded protein response

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Endorribonucleases Limite: Animals / Humans Idioma: En Revista: Circ Res Ano de publicação: 2022 Tipo de documento: Article

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