Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells.

Lei, Sisi; Feng, Yuchao; Huang, Peiying; Chen, BoJun; Bao, Kun; Wu, Qihua; Zhang, Haobo; Huang, Xiaoyan

Lei, Sisi; Feng, Yuchao; Huang, Peiying; Chen, BoJun; Bao, Kun; Wu, Qihua; Zhang, Haobo; Huang, Xiaoyan.

Afiliação

Lei S; The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510006, China; Guangdong Provincial Key Laboratory of Research on Emergency in Traditional Chinese Medicine, Clinical Research Team of Prevention and Treatment of Cardiac Emergencies with Traditional Chinese M
Feng Y; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China; Guangdong Provincial Key Laboratory of Research on Emergency in Traditional Chinese Medicine, Clinical Research Team of Prevention and Treatment of Cardiac Emergencies with Traditional Chinese Medici
Huang P; The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510006, China; Guangdong Provincial Key Laboratory of Research on Emergency in Traditional Chinese Medicine, Clinical Research Team of Prevention and Treatment of Cardiac Emergencies with Traditional Chinese M
Chen B; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China; Guangdong Provincial Key Laboratory of Research on Emergency in Traditional Chinese Medicine, Clinical Research Team of Prevention and Treatment of Cardiac Emergencies with Traditional Chinese Medici
Bao K; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Wu Q; The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510006, China; Guangdong Provincial Key Laboratory of Research on Emergency in Traditional Chinese Medicine, Clinical Research Team of Prevention and Treatment of Cardiac Emergencies with Traditional Chinese M
Zhang H; The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510006, China; Guangdong Provincial Key Laboratory of Research on Emergency in Traditional Chinese Medicine, Clinical Research Team of Prevention and Treatment of Cardiac Emergencies with Traditional Chinese M
Huang X; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China; Guangdong Provincial Key Laboratory of Research on Emergency in Traditional Chinese Medicine, Clinical Research Team of Prevention and Treatment of Cardiac Emergencies with Traditional Chinese Medici

Toxicology ; 477: 153275, 2022 07.

Article em En | MEDLINE | ID: mdl-35905946

Assuntos

Cardiotoxicidade; Mitofagia; Humanos; Proteínas Quinases/metabolismo; Saponinas; Transdução de Sinais; Espirostanos; Ubiquitina-Proteína Ligases/metabolismo

Palavras-chave

Cardiomyocytes; Mitochondrial toxicity; Mitophagy; Ophiopogonin D'; PINK1/Parkin

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Mitofagia / Cardiotoxicidade Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Toxicology Ano de publicação: 2022 Tipo de documento: Article

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