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Treatment time and circadian genotype interact to influence radiotherapy side-effects. A prospective European validation study using the REQUITE cohort.
Webb, Adam J; Harper, Emily; Rattay, Tim; Aguado-Barrera, Miguel E; Azria, David; Bourgier, Celine; Brengues, Muriel; Briers, Erik; Bultijnck, Renée; Chang-Claude, Jenny; Choudhury, Ananya; Cicchetti, Alessandro; De Ruysscher, Dirk; De Santis, Maria Carmen; Dunning, Alison M; Elliott, Rebecca M; Fachal, Laura; Gómez-Caamaño, Antonio; Gutiérrez-Enríquez, Sara; Johnson, Kerstie; Lobato-Busto, Ramón; Kerns, Sarah L; Post, Giselle; Rancati, Tiziana; Reyes, Victoria; Rosenstein, Barry S; Seibold, Petra; Seoane, Alejandro; Sosa-Fajardo, Paloma; Sperk, Elena; Taboada-Valladares, Begoña; Valdagni, Riccardo; Vega, Ana; Veldeman, Liv; Ward, Tim; West, Catharine M; Symonds, R Paul; Talbot, Christopher J.
Afiliação
  • Webb AJ; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK.
  • Harper E; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK.
  • Rattay T; Leicester Cancer Research Centre, University of Leicester, Leicester, UK.
  • Aguado-Barrera ME; Fundación Pública Galega Medicina Xenómica, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain.
  • Azria D; Department of Radiation Oncology, Montpellier Cancer Institute, Université Montpellier, Inserm U1194, Montpellier, France.
  • Bourgier C; Department of Radiation Oncology, Montpellier Cancer Institute, Université Montpellier, Inserm U1194, Montpellier, France.
  • Brengues M; Institut de Recherche en Cancérologie de Montpellier, Université Montpellier, Inserm U1194, Montpellier, France.
  • Briers E; Patient advocate, Hasselt, Belgium.
  • Bultijnck R; Department of Human Structure and Repair, Ghent University, Ghent, Belgium.
  • Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Choudhury A; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester, UK.
  • Cicchetti A; Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • De Ruysscher D; Maastricht University Medical Center, Department of Radiation Oncology (Maastro clinic), GROW School for Oncology and Developmental Biology, Maastricht, the Netherlands.
  • De Santis MC; Department of Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Elliott RM; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester, UK.
  • Fachal L; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
  • Gómez-Caamaño A; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.
  • Gutiérrez-Enríquez S; Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
  • Johnson K; Leicester Cancer Research Centre, University of Leicester, Leicester, UK.
  • Lobato-Busto R; Department of Medical Physics, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.
  • Kerns SL; Departments of Radiation Oncology and Surgery, University of Rochester Medical Center, Rochester, New York, NY, United States.
  • Post G; Department of Human Structure and Repair, Ghent University, Ghent, Belgium.
  • Rancati T; Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Reyes V; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
  • Rosenstein BS; Department of Radiation Oncology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Seibold P; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Seoane A; Medical Physics Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
  • Sosa-Fajardo P; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.
  • Sperk E; Department of Radiation Oncology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
  • Taboada-Valladares B; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.
  • Valdagni R; Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Oncology and Haematology-Oncology, Universita degli Studi di Milano, Italy.
  • Vega A; Fundación Pública Galega Medicina Xenómica, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain; Biomedical Network on Rare Diseases (CIBERER), Spain.
  • Veldeman L; Department of Human Structure and Repair, Ghent University, Ghent, Belgium; Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium.
  • Ward T; Patient advocate, NCRI CTRad consumer, UK.
  • West CM; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester, UK.
  • Symonds RP; Leicester Cancer Research Centre, University of Leicester, Leicester, UK.
  • Talbot CJ; Leicester Cancer Research Centre, University of Leicester, Leicester, UK. Electronic address: cjt14@le.ac.uk.
EBioMedicine ; 84: 104269, 2022 Oct.
Article em En | MEDLINE | ID: mdl-36130474
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tratamento / Radioterapia Base de dados: MEDLINE Assunto principal: Lesões por Radiação / Proteínas Circadianas Period Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: EBioMedicine Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tratamento / Radioterapia Base de dados: MEDLINE Assunto principal: Lesões por Radiação / Proteínas Circadianas Period Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: EBioMedicine Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido