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Concurrent inhibition of CDK2 adds to the anti-tumour activity of CDK4/6 inhibition in GIST.
Schaefer, Inga-Marie; Hemming, Matthew L; Lundberg, Meijun Z; Serrata, Matthew P; Goldaracena, Isabel; Liu, Ninning; Yin, Peng; Paulo, Joao A; Gygi, Steven P; George, Suzanne; Morgan, Jeffrey A; Bertagnolli, Monica M; Sicinska, Ewa T; Chu, Chen; Zheng, Shanshan; Mariño-Enríquez, Adrian; Hornick, Jason L; Raut, Chandrajit P; Ou, Wen-Bin; Demetri, George D; Saka, Sinem K; Fletcher, Jonathan A.
Afiliação
  • Schaefer IM; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. ischaefer@bwh.harvard.edu.
  • Hemming ML; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
  • Lundberg MZ; Sarcoma Center, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Serrata MP; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Goldaracena I; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
  • Liu N; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
  • Yin P; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
  • Paulo JA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
  • Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • George S; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Morgan JA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
  • Bertagnolli MM; Sarcoma Center, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Sicinska ET; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
  • Chu C; Sarcoma Center, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Zheng S; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Mariño-Enríquez A; Department of Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Hornick JL; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Raut CP; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Ou WB; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Demetri GD; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Saka SK; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Fletcher JA; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Br J Cancer ; 127(11): 2072-2085, 2022 11.
Article em En | MEDLINE | ID: mdl-36175617
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Tumores do Estroma Gastrointestinal / Neoplasias Gastrointestinais Limite: Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Tumores do Estroma Gastrointestinal / Neoplasias Gastrointestinais Limite: Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos