Conception and pregnancy outcome after laparoscopic treatment of subtle distal fallopian tube abnormalities in infertile women: a prospective cohort study.
Reprod Biomed Online
; 45(6): 1230-1236, 2022 12.
Article
em En
| MEDLINE
| ID: mdl-36274014
ABSTRACT
RESEARCH QUESTION What are conception rates and pregnancy outcomes after laparoscopic treatment of subtle distal tubal abnormalities among infertile women, and which factors relate to natural conception? DESIGN:
Prospective cohort study (nâ¯=â¯234) conducted in a single fertility referral centre between January 2017 and December 2018. Subtle abnormalities included fimbrial agglutination, tubal diverticula, accessory ostium, fimbrial phimosis and accessory fallopian tube. Pregnancy outcomes were followed-up annually until 36 months.RESULTS:
One hundred and nine patients conceived naturally (natural conception rate 46.6%), and 59 patients conceived after IVF. Term live birth rate of the natural conception group was significantly higher than the IVF conception group (86.2% versus 71.2%, chi-squaredâ¯=â¯5.625, Pâ¯=â¯0.018). Preterm birth (11.9% versus 0%, Pâ¯=â¯0.001) and multiple pregnancy rates (27.1% versus 0%, P < 0.001) of the IVF conception group were significantly higher than the natural conception group. Patient age (hazard ratioâ¯=â¯0.917, 95% CI 0.870 to 0.967, Pâ¯=â¯0.001), duration of infertility (hazard ratioâ¯=â¯0.846, 95% CI 0.740 to 0.966, Pâ¯=â¯0.014) and concurrent types of subtle abnormalities (hazard ratioâ¯=â¯0.636, 95% CI 0.416 to 0.970, Pâ¯=â¯0.036) were factors associated with natural conception.CONCLUSIONS:
Laparoscopy is an effective treatment for infertile patients with subtle abnormalities, especially for young patients with a short infertile period and at most two types of subtle abnormalities. For older women, a long infertile period and more than two types of subtle abnormalities, IVF may be more suitable after laparoscopic diagnosis.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Laparoscopia
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Nascimento Prematuro
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Doenças das Tubas Uterinas
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Infertilidade Feminina
Tipo de estudo:
Etiology_studies
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Observational_studies
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Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Newborn
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Pregnancy
Idioma:
En
Revista:
Reprod Biomed Online
Assunto da revista:
MEDICINA REPRODUTIVA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China