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Directed evolution identifies high-affinity cystine-knot peptide agonists and antagonists of Wnt/ß-catenin signaling.
Hansen, Simon; Zhang, Yingnan; Hwang, Sunhee; Nabhan, Ahmad; Li, Wanqing; Fuhrmann, Jakob; Kschonsak, Yvonne; Zhou, Lijuan; Nile, Aaron H; Gao, Xinxin; Piskol, Robert; de Sousa E Melo, Felipe; de Sauvage, Frederic J; Hannoush, Rami N.
Afiliação
  • Hansen S; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA.
  • Zhang Y; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA.
  • Hwang S; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA.
  • Nabhan A; Department of Physiological Chemistry, Genentech, South San Francisco, CA.
  • Li W; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA.
  • Fuhrmann J; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA.
  • Kschonsak Y; Department of Molecular Oncology, Genentech, South San Francisco, CA.
  • Zhou L; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA.
  • Nile AH; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA.
  • Gao X; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA.
  • Piskol R; Department of Molecular Oncology, Genentech, South San Francisco, CA.
  • de Sousa E Melo F; Department of Molecular Oncology, Genentech, South San Francisco, CA.
  • de Sauvage FJ; Department of Molecular Oncology, Genentech, South San Francisco, CA.
  • Hannoush RN; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA.
Proc Natl Acad Sci U S A ; 119(46): e2207327119, 2022 11 16.
Article em En | MEDLINE | ID: mdl-36343233
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Beta Catenina / Via de Sinalização Wnt Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Beta Catenina / Via de Sinalização Wnt Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá