BCAT1, as a prognostic factor for HCC, can promote the development of liver cancer through activation of the AKT signaling pathway and EMT.

Ding, Yifeng; Wang, Xiaoqing; Lu, Shaowei; Lai, Aijun; Xie, Binhui; He, Xiao; Liu, Qingquan

Ding, Yifeng; Wang, Xiaoqing; Lu, Shaowei; Lai, Aijun; Xie, Binhui; He, Xiao; Liu, Qingquan.

Afiliação

Ding Y; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Wang X; Department of Psychiatry, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Lu S; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Lai A; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Xie B; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
He X; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Liu Q; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, Jiangxi, China. liuqingquan918@163.com.

J Mol Histol ; 54(1): 25-39, 2023 Feb.

Article em En | MEDLINE | ID: mdl-36344754

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; Humanos; Carcinoma Hepatocelular/genética; Neoplasias Hepáticas/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Prognóstico; Transição Epitelial-Mesenquimal/genética; Linhagem Celular Tumoral; Transdução de Sinais; Movimento Celular/genética; Regulação Neoplásica da Expressão Gênica; Transaminases/genética; Transaminases/metabolismo

Palavras-chave

AKT (protein kinase B); BCAT1; EMT; HCC; Mechanism; Prognosis

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Mol Histol Assunto da revista: HISTOCITOQUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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