Psychological Distress in Young Adults with Acute Myeloid Leukemia Undergoing Induction Chemotherapy.
J Adolesc Young Adult Oncol
; 12(4): 592-598, 2023 08.
Article
em En
| MEDLINE
| ID: mdl-36367711
ABSTRACT
Young adults (YAs), aged 18-39 years, with acute myeloid leukemia (AML) navigate life disruptions amid an unpredictable illness trajectory. We conducted a secondary analysis of patient-reported outcomes for hospitalized YAs with high-risk AML receiving intensive chemotherapy, collected during a multisite randomized clinical trial. Of the 160 patients, 14 (8.8%) were YAs. At week 2 of hospitalization, YAs demonstrated significant worse quality of life (ß = -18.27; p = 0.036), higher anxiety (ß = 2.72; p = 0.048), and higher post-traumatic stress disorder (PTSD; ß = 10.34; p = 0.007) compared with older adults. Our analysis demonstrated a longitudinal presence of anxiety and PTSD, suggesting persistent unmet psychological needs for YAs with AML.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Cuidados_paliativos
/
Geral
/
Tipos_de_cancer
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Leucemia
Base de dados:
MEDLINE
Assunto principal:
Leucemia Mieloide Aguda
/
Angústia Psicológica
Tipo de estudo:
Clinical_trials
Limite:
Adult
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Aged
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Humans
Idioma:
En
Revista:
J Adolesc Young Adult Oncol
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos