Impact of ATP-citrate lyase catalytic activity and serine 455 phosphorylation on histone acetylation and inflammatory responses in human monocytic THP-1 cells.

Dominguez, Monica; Truemper, Verena; Mota, Ana Carolina; Brüne, Bernhard; Namgaladze, Dmitry

Dominguez, Monica; Truemper, Verena; Mota, Ana Carolina; Brüne, Bernhard; Namgaladze, Dmitry.

Afiliação

Dominguez M; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
Truemper V; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
Mota AC; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
Brüne B; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
Namgaladze D; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Frankfurt, Germany.

Front Immunol ; 13: 906127, 2022.

Article em En | MEDLINE | ID: mdl-36439127

Assuntos

Histonas; Serina; Humanos; Acetilação; Fosforilação; Células THP-1; Histonas/metabolismo; Serina/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Lipopolissacarídeos/metabolismo; ATP Citrato (pro-S)-Liase/metabolismo; Trifosfato de Adenosina/metabolismo

Palavras-chave

ATP-citrate lyase; histone acetylation; inflammation; macrophages; metabolism

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Serina / Histonas Limite: Humans Idioma: En Revista: Front Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha

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