Multiplex immunofluorescence and single-cell transcriptomic profiling reveal the spatial cell interaction networks in the non-small cell lung cancer microenvironment.

Peng, Haoxin; Wu, Xiangrong; Liu, Shaopeng; He, Miao; Xie, Chao; Zhong, Ran; Liu, Jun; Tang, Chenshuo; Li, Caichen; Xiong, Shan; Zheng, Hongbo; He, Jianxing; Lu, Xu; Liang, Wenhua

Peng, Haoxin; Wu, Xiangrong; Liu, Shaopeng; He, Miao; Xie, Chao; Zhong, Ran; Liu, Jun; Tang, Chenshuo; Li, Caichen; Xiong, Shan; Zheng, Hongbo; He, Jianxing; Lu, Xu; Liang, Wenhua.

Afiliação

Peng H; Department of Thoracic Oncology and Surgery, China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Wu X; Department of Clinical Medicine, Nanshan School, Guangzhou Medical University, Guangzhou, China.
Liu S; Department of Thoracic Oncology and Surgery, China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
He M; Department of Clinical Medicine, Nanshan School, Guangzhou Medical University, Guangzhou, China.
Xie C; Department of Computer Science, Guangdong Polytechnic Normal University, Guangzhou, China.
Zhong R; Department of Artificial Intelligence Research, Pazhou Lab, Guangzhou, China.
Liu J; Department of Thoracic Oncology and Surgery, China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Tang C; Department of Computer Science, Guangdong Polytechnic Normal University, Guangzhou, China.
Li C; Department of Thoracic Oncology and Surgery, China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xiong S; Department of Thoracic Oncology and Surgery, China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zheng H; Department of Computer Science, Guangdong Polytechnic Normal University, Guangzhou, China.
He J; Department of Thoracic Oncology and Surgery, China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Lu X; Department of Thoracic Oncology and Surgery, China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Liang W; Medical Department, Genecast Biotechnology Co., Ltd, Beijing, China.

Clin Transl Med ; 13(1): e1155, 2023 01.

Article em En | MEDLINE | ID: mdl-36588094

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Neoplasias Pulmonares; Humanos; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/patologia; Neoplasias Pulmonares/patologia; Transcriptoma; Microambiente Tumoral/genética; Imunofluorescência

Palavras-chave

cell interaction networks; deep learning algorithm; multiplex immunofluorescence; single-cell RNA sequencing; tumour microenvironment

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pulmao Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Transl Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google