Obeticholic acid and 5ß-cholanic acid 3 exhibit anti-tumor effects on liver cancer through CXCL16/CXCR6 pathway.

Gou, Haoxian; Liu, Shenglu; Liu, Linxin; Luo, Ming; Qin, Shu; He, Kai; Yang, Xiaoli

Gou, Haoxian; Liu, Shenglu; Liu, Linxin; Luo, Ming; Qin, Shu; He, Kai; Yang, Xiaoli.

Afiliação

Gou H; Department of Hepatobiliary Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Liu S; Academician Workstation of Sichuan Province, Luzhou, China.
Liu L; Academician Workstation of Sichuan Province, Luzhou, China.
Luo M; Department of Hepatobiliary Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Qin S; Academician Workstation of Sichuan Province, Luzhou, China.
He K; Academician Workstation of Sichuan Province, Luzhou, China.
Yang X; Department of Hepatobiliary Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

Front Immunol ; 13: 1095915, 2022.

Article em En | MEDLINE | ID: mdl-36605219

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; Camundongos; Animais; Humanos; Neoplasias Hepáticas/tratamento farmacológico; Neoplasias Hepáticas/patologia; Carcinoma Hepatocelular/tratamento farmacológico; Células Endoteliais/metabolismo; Receptores CXCR6/metabolismo; Camundongos Endogâmicos C57BL; Quimiocina CXCL16

Palavras-chave

CXCL16; bile acids; hepatocellular carcinoma; immunotherapy; natural killer T cells; single cell RNA sequencing

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Limite: Animals / Humans Idioma: En Revista: Front Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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