Antiretroviral APOBEC3 cytidine deaminases alter HIV-1 provirus integration site profiles.

Ajoge, Hannah O; Renner, Tyler M; Bélanger, Kasandra; Greig, Matthew; Dankar, Samar; Kohio, Hinissan P; Coleman, Macon D; Ndashimye, Emmanuel; Arts, Eric J; Langlois, Marc-André; Barr, Stephen D

Ajoge, Hannah O; Renner, Tyler M; Bélanger, Kasandra; Greig, Matthew; Dankar, Samar; Kohio, Hinissan P; Coleman, Macon D; Ndashimye, Emmanuel; Arts, Eric J; Langlois, Marc-André; Barr, Stephen D.

Afiliação

Ajoge HO; Western University, Schulich School of Medicine and Dentistry, Department of Microbiology and Immunology, London, ON, Canada.
Renner TM; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Bélanger K; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Greig M; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Dankar S; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Kohio HP; Western University, Schulich School of Medicine and Dentistry, Department of Microbiology and Immunology, London, ON, Canada.
Coleman MD; Western University, Schulich School of Medicine and Dentistry, Department of Microbiology and Immunology, London, ON, Canada.
Ndashimye E; Western University, Schulich School of Medicine and Dentistry, Department of Microbiology and Immunology, London, ON, Canada.
Arts EJ; Western University, Schulich School of Medicine and Dentistry, Department of Microbiology and Immunology, London, ON, Canada.
Langlois MA; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada. langlois@uottawa.ca.
Barr SD; Ottawa Center for Infection, Immunity and Inflammation (CI3), Ottawa, ON, Canada. langlois@uottawa.ca.

Nat Commun ; 14(1): 16, 2023 01 10.

Article em En | MEDLINE | ID: mdl-36627271

Assuntos

Infecções por HIV; HIV-1; Humanos; Citidina Desaminase/genética; Citidina Desaminase/metabolismo; HIV-1/genética; HIV-1/metabolismo; Desaminase APOBEC-3G/metabolismo; Citosina Desaminase/genética; Citosina Desaminase/metabolismo; Proteínas/metabolismo; Antirretrovirais; Integração Viral/genética; Citidina/metabolismo; Desaminases APOBEC/genética; Desaminases APOBEC/metabolismo

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá

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