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An NIR fluorescent/photoacoustic dual-mode probe of NADPH for tumor imaging.
Guan, Liandi; Hu, Wanting; Zuo, Hongzhi; Sun, Hua; Ai, Yongjian; He, Meng-Qi; Ma, Cheng; Ding, Mingyu; Liang, Qionglin.
Afiliação
  • Guan L; MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Laboratory of Flexible Electronics Technology, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, P. R. China. dingmy@mail.tsinghua.edu.cn.
  • Hu W; MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Laboratory of Flexible Electronics Technology, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, P. R. China. dingmy@mail.tsinghua.edu.cn.
  • Zuo H; Department of Electronic Engineering, Tsinghua University, Beijing 100084, China. cheng_ma@tsinghua.edu.cn.
  • Sun H; MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Laboratory of Flexible Electronics Technology, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, P. R. China. dingmy@mail.tsinghua.edu.cn.
  • Ai Y; MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Laboratory of Flexible Electronics Technology, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, P. R. China. dingmy@mail.tsinghua.edu.cn.
  • He MQ; MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Laboratory of Flexible Electronics Technology, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, P. R. China. dingmy@mail.tsinghua.edu.cn.
  • Ma C; Department of Electronic Engineering, Tsinghua University, Beijing 100084, China. cheng_ma@tsinghua.edu.cn.
  • Ding M; MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Laboratory of Flexible Electronics Technology, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, P. R. China. dingmy@mail.tsinghua.edu.cn.
  • Liang Q; MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Laboratory of Flexible Electronics Technology, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, P. R. China. dingmy@mail.tsinghua.edu.cn.
Chem Commun (Camb) ; 59(12): 1617-1620, 2023 Feb 07.
Article em En | MEDLINE | ID: mdl-36661262
ABSTRACT
A novel probe was synthesized with a turn-on NIR fluorescent (NIRF)/photoacoustic (PA) response to NADPH, which was successfully applied in both monitoring intracellular NADPH and dual-modal imaging of tumor-bearing mice. It exhibits good potential in studying and understanding the tumor energy metabolism and treatment process related to NADPH.
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Técnicas Fotoacústicas / Neoplasias Limite: Animals Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Técnicas Fotoacústicas / Neoplasias Limite: Animals Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article