C-Terminal p53 Palindromic Tetrapeptide Restores Full Apoptotic Function to Mutant p53 Cancer Cells In Vitro and In Vivo.

Fine, Robert L; Mao, Yuehua; Dinnen, Richard; Rosal, Ramon V; Raffo, Anthony; Hochfeld, Uri; Senatus, Patrick; Bruce, Jeffrey N; Nichols, Gwen; Wang, Hsin; Li, Yongliang; Brandt-Rauf, Paul W

Fine, Robert L; Mao, Yuehua; Dinnen, Richard; Rosal, Ramon V; Raffo, Anthony; Hochfeld, Uri; Senatus, Patrick; Bruce, Jeffrey N; Nichols, Gwen; Wang, Hsin; Li, Yongliang; Brandt-Rauf, Paul W.

Afiliação

Fine RL; Experimental Therapeutics Program, Division of Medical Oncology, College of Physicians and Surgeons of Columbia University, New York, NY 10314, USA.
Mao Y; Experimental Therapeutics Program, Division of Medical Oncology, College of Physicians and Surgeons of Columbia University, New York, NY 10314, USA.
Dinnen R; Experimental Therapeutics Program, Division of Medical Oncology, College of Physicians and Surgeons of Columbia University, New York, NY 10314, USA.
Rosal RV; Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, NY 10314, USA.
Raffo A; Experimental Therapeutics Program, Division of Medical Oncology, College of Physicians and Surgeons of Columbia University, New York, NY 10314, USA.
Hochfeld U; Experimental Therapeutics Program, Division of Medical Oncology, College of Physicians and Surgeons of Columbia University, New York, NY 10314, USA.
Senatus P; Department of Neurosurgery, Neurologic Institute of New York, Columbia University Medical Center, New York, NY 10032, USA.
Bruce JN; Department of Neurosurgery, Neurologic Institute of New York, Columbia University Medical Center, New York, NY 10032, USA.
Nichols G; Experimental Therapeutics Program, Division of Medical Oncology, College of Physicians and Surgeons of Columbia University, New York, NY 10314, USA.
Wang H; Department of Chemistry, College of Staten Island, 2800 Victory Boulevard, New York, NY 10314, USA.
Li Y; Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, NY 10314, USA.
Brandt-Rauf PW; Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, NY 10314, USA.

Biomedicines ; 11(1)2023 Jan 05.

Article em En | MEDLINE | ID: mdl-36672645

Palavras-chave

Bax; Fas; ROS; apoptosis; breast cancer; p53; p53 peptide

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Idioma: En Revista: Biomedicines Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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