Mutations involving TGFB and MAPK may be associated with malignancy in granular cell tumors.

Dehner, Carina A; Moon, Tyler; Lyu, Yang; Zhang, Xiaochun; Zhou, Zhaohe; Yang, Kuangying; Chrisinger, John S A; Griffin, Anthony; Wunder, Jay; Dickson, Brendan C; Hirbe, Angela C

Dehner, Carina A; Moon, Tyler; Lyu, Yang; Zhang, Xiaochun; Zhou, Zhaohe; Yang, Kuangying; Chrisinger, John S A; Griffin, Anthony; Wunder, Jay; Dickson, Brendan C; Hirbe, Angela C.

Afiliação

Dehner CA; Department of Pathology and Immunology, Division of Anatomic Pathology, Washington University School of Medicine, St. Louis, Missouri, USA.
Moon T; Department of Orthopedic Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Lyu Y; Department of Medicine, Division of Oncology, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA.
Zhang X; Department of Medicine, Division of Oncology, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA.
Zhou Z; Department of Medicine, Division of Oncology, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA.
Yang K; Department of Medicine, Division of Oncology, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA.
Chrisinger JSA; Department of Pathology and Immunology, Division of Anatomic Pathology, Washington University School of Medicine, St. Louis, Missouri, USA.
Griffin A; University Musculoskeletal Oncology Unit, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
Wunder J; University Musculoskeletal Oncology Unit, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
Dickson BC; Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Hirbe AC; Department of Medicine, Division of Oncology, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA.

Genes Chromosomes Cancer ; 62(5): 301-307, 2023 05.

Article em En | MEDLINE | ID: mdl-36680529

Assuntos

Tumor de Células Granulares; Humanos; Tumor de Células Granulares/genética; Mutação; Fator de Crescimento Transformador beta/genética; Proteínas Quinases Ativadas por Mitógeno/metabolismo

Palavras-chave

MAPK; TGFß; granular cell tumor; malignant transformation; sarcoma

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Tumor de Células Granulares Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Genes Chromosomes Cancer Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google