Three-dimensional mouse cochlea imaging based on the modified Sca/eS using confocal microscopy.
Anat Sci Int
; 98(3): 309-317, 2023 Jul.
Article
em En
| MEDLINE
| ID: mdl-36773194
ABSTRACT
The three-dimensional stria vascularis (SV) and cochlear blood vessel structure is essential for inner ear function. Here, modified Sca/eS, a sorbitol-based optical-clearing method, was reported to visualize SV and vascular structure in the intact mouse cochlea. Cochlear macrophages as well as perivascular-resident macrophage-like melanocytes were detected as GFP-positive cells of the CX3CR1+/GFP mice. This study's method was effective in elucidating inner ear function under both physiological and pathological conditions.
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Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Cóclea
/
Orelha Interna
Limite:
Animals
Idioma:
En
Revista:
Anat Sci Int
Assunto da revista:
ANATOMIA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Japão