Cell State Transitions and Phenotypic Heterogeneity in Luminal Breast Cancer Implicating MicroRNAs as Potential Regulators.

Richard, Vinitha; Nair, Madhumathy G; Jaikumar, Vishnu S; Jones, Sara; Prabhu, Jyothi S; Kerin, Michael J

Richard, Vinitha; Nair, Madhumathy G; Jaikumar, Vishnu S; Jones, Sara; Prabhu, Jyothi S; Kerin, Michael J.

Afiliação

Richard V; Discipline of Surgery, Lambe Institute for Translational Research, University of Galway, H91 V4AY Galway, Ireland.
Nair MG; Division of Molecular Medicine, St. John's Research Institute, Bangalore 560034, Karnataka, India.
Jaikumar VS; Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695585, Kerala, India.
Jones S; Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695585, Kerala, India.
Prabhu JS; Division of Molecular Medicine, St. John's Research Institute, Bangalore 560034, Karnataka, India.
Kerin MJ; Discipline of Surgery, Lambe Institute for Translational Research, University of Galway, H91 V4AY Galway, Ireland.

Int J Mol Sci ; 24(4)2023 Feb 09.

Article em En | MEDLINE | ID: mdl-36834918

Assuntos

Neoplasias da Mama; MicroRNAs; Humanos; Animais; Camundongos; Feminino; Neoplasias da Mama/metabolismo; MicroRNAs/genética; Receptor ErbB-2/metabolismo; Trastuzumab/uso terapêutico; Mama/metabolismo; Fenótipo; Receptores de Progesterona/genética

Palavras-chave

cancer stem cells; drug transporter proteins; hormone receptors; intratumoral heterogeneity; luminal breast cancer; microRNA; phenotypic transition; side population cells; tumor subtypes; tumorigenic potential

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / MicroRNAs Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irlanda

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