Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats.

Sharaf, Gehad; E M, El Morsy; El-Sayed, Elsayed K

Sharaf, Gehad; E M, El Morsy; El-Sayed, Elsayed K.

Afiliação

Sharaf G; Nasr Hospital Health Insurance, Helwan, Cairo, Egypt. Electronic address: gehadsharfelgebaly@gmail.com.
E M EM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Helwan University, Cairo, Egypt. Electronic address: elmorsy_em@pharm.helwan.edu.eg.
El-Sayed EK; Pharmacology and Toxicology Department, Faculty of Pharmacy, Helwan University, Cairo, Egypt. Electronic address: elsayed_elsayed@pharm.helwan.edu.eg.

Life Sci ; 321: 121609, 2023 May 15.

Article em En | MEDLINE | ID: mdl-36958435

Assuntos

Cisplatino; Liraglutida; Ratos; Animais; Cisplatino/toxicidade; Cisplatino/metabolismo; Liraglutida/farmacologia; Liraglutida/metabolismo; Rabeprazol/farmacologia; Rim/metabolismo; Estresse Oxidativo; Proteínas Quinases Ativadas por Mitógeno/metabolismo; Apoptose

Palavras-chave

Cisplatin; Liraglutide; MAPK; Nephrotoxicity; OCT2 and GLP-1; Rabeprazole

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Cisplatino / Liraglutida Limite: Animals Idioma: En Revista: Life Sci Ano de publicação: 2023 Tipo de documento: Article

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