Transglutaminase 2 Binds to the CD44v6 Cytoplasmic Domain to Stimulate CD44v6/ERK1/2 Signaling and Maintain an Aggressive Cancer Phenotype.

Chen, Xi; Adhikary, Gautam; Newland, John J; Xu, Wen; Keillor, Jeffrey W; Weber, David J; Eckert, Richard L

Chen, Xi; Adhikary, Gautam; Newland, John J; Xu, Wen; Keillor, Jeffrey W; Weber, David J; Eckert, Richard L.

Afiliação

Chen X; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland.
Adhikary G; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland.
Newland JJ; Department of Surgery Division of Thoracic Oncology, University of Maryland School of Medicine, Baltimore, Maryland.
Xu W; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland.
Keillor JW; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.
Weber DJ; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland.
Eckert RL; Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.

Mol Cancer Res ; 21(9): 922-932, 2023 09 01.

Article em En | MEDLINE | ID: mdl-37227250

Assuntos

Neoplasias; Proteína 2 Glutamina gama-Glutamiltransferase; Humanos; Linhagem Celular Tumoral; Proteínas de Ligação ao GTP/genética; Proteínas de Ligação ao GTP/metabolismo; Sistema de Sinalização das MAP Quinases; Neoplasias/metabolismo; Neoplasias/patologia; Fenótipo; Proteína 2 Glutamina gama-Glutamiltransferase/metabolismo

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Proteína 2 Glutamina gama-Glutamiltransferase / Neoplasias Limite: Humans Idioma: En Revista: Mol Cancer Res Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2023 Tipo de documento: Article

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