Rational design of a ratiometric fluorescent probe for imaging lysosomal nitroreductase activity.

Bai, Wenjun; Li, Yixuan; Zhao, Li; Li, Ruxin; Geng, Jiahou; Lu, Yang; Zhao, Yufen; Wang, Jinhui

Bai, Wenjun; Li, Yixuan; Zhao, Li; Li, Ruxin; Geng, Jiahou; Lu, Yang; Zhao, Yufen; Wang, Jinhui.

Afiliação

Bai W; Institute of Drug Discovery Technology, Ningbo University, Ningbo, China.
Li Y; Faculty of Materials Science and Chemical Engineering, Ningbo University, Ningbo, China.
Zhao L; Institute of Drug Discovery Technology, Ningbo University, Ningbo, China.
Li R; Institute of Drug Discovery Technology, Ningbo University, Ningbo, China.
Geng J; Institute of Drug Discovery Technology, Ningbo University, Ningbo, China.
Lu Y; Institute of Drug Discovery Technology, Ningbo University, Ningbo, China. Electronic address: luyang@nbu.edu.cn.
Zhao Y; Institute of Drug Discovery Technology, Ningbo University, Ningbo, China; Qian Xuesen Collaborative Research Center of Astrochemistry and Space Life Sciences, Ningbo University, Ningbo, China.
Wang J; Institute of Drug Discovery Technology, Ningbo University, Ningbo, China; Qian Xuesen Collaborative Research Center of Astrochemistry and Space Life Sciences, Ningbo University, Ningbo, China. Electronic address: wangjinhui@nbu.edu.cn.

Spectrochim Acta A Mol Biomol Spectrosc ; 302: 123032, 2023 Dec 05.

Article em En | MEDLINE | ID: mdl-37356386

Assuntos

Corantes Fluorescentes; Lisossomos; Humanos; Corantes Fluorescentes/química; Microscopia de Fluorescência; Linhagem Celular Tumoral; Nitrorredutases/química; Imagem Óptica/métodos

Palavras-chave

Lysosome imaging; Nitroreductase responsive; Ratiometric; Triphenylamine

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Corantes Fluorescentes / Lisossomos Limite: Humans Idioma: En Revista: Spectrochim Acta A Mol Biomol Spectrosc Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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