Directed differentiation of human hindbrain neuroepithelial stem cells recapitulates cerebellar granule neurogenesis.

Dave, Biren M; Chen, Xin; McCready, Fraser; Charton, Connor S; Morley, Rachel M; Tailor, Jignesh K; Ellis, James; Huang, Xi; Dirks, Peter B

Dave, Biren M; Chen, Xin; McCready, Fraser; Charton, Connor S; Morley, Rachel M; Tailor, Jignesh K; Ellis, James; Huang, Xi; Dirks, Peter B.

Afiliação

Dave BM; Department of Molecular Genetics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S1A8, Canada.
Chen X; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G0A4, Canada.
McCready F; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G0A4, Canada.
Charton CS; Songjiang Research Institute, Songjiang Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China.
Morley RM; Department of Molecular Genetics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S1A8, Canada.
Tailor JK; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G0A4, Canada.
Ellis J; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G0A4, Canada.
Huang X; Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S1A8, Canada.
Dirks PB; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G0A4, Canada.

Development ; 150(13)2023 07 01.

Article em En | MEDLINE | ID: mdl-37381820

Assuntos

Cerebelo; Proteínas Hedgehog; Humanos; Proteínas Hedgehog/metabolismo; Rombencéfalo/metabolismo; Diferenciação Celular/fisiologia; Neurogênese; Células-Tronco

Palavras-chave

Cerebellum; Differentiation; Granule neuron lineage; Neuroepithelial stem cells; Sonic hedgehog

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Cerebelo / Proteínas Hedgehog Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Development Assunto da revista: BIOLOGIA / EMBRIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá

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