Application of peptide barcoding to obtain high-affinity anti-PD-1 nanobodies.

Miyazaki, Takumi; Aoki, Wataru; Koike, Naoki; Sato, Toshiko; Ueda, Mitsuyoshi

Miyazaki, Takumi; Aoki, Wataru; Koike, Naoki; Sato, Toshiko; Ueda, Mitsuyoshi.

Afiliação

Miyazaki T; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.
Aoki W; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan; Kyoto Integrated Science and Technology Bio-Analysis Center, Simogyo-ku, Kyoto 600-8813, Japan. Electronic address: aoki.wataru@bio.eng.osaka-u.ac.jp.
Koike N; TechnoPro, Inc. TechnoPro R&D, Company, Tokyo 106-6135, Japan.
Sato T; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.
Ueda M; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan; Kyoto Integrated Science and Technology Bio-Analysis Center, Simogyo-ku, Kyoto 600-8813, Japan.

J Biosci Bioeng ; 136(3): 173-181, 2023 Sep.

Article em En | MEDLINE | ID: mdl-37487915

Assuntos

Antineoplásicos; Anticorpos de Domínio Único; Anticorpos de Domínio Único/química; Inibidores de Checkpoint Imunológico; Peptídeos/química; Biblioteca de Peptídeos

Palavras-chave

Immune checkpoint inhibitor; Mass spectrometry; Nanobody; Peptide barcode; Programmed cell death-1; Screening; Size-exclusion chromatography

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Anticorpos de Domínio Único / Antineoplásicos Tipo de estudo: Prognostic_studies Idioma: En Revista: J Biosci Bioeng Assunto da revista: ENGENHARIA BIOMEDICA / MICROBIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

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