Emodin improves glucose metabolism and ovarian function in PCOS mice via the HMGB1/TLR4/NF-&#954;B molecular pathway.

Otoo, Antonia; Czika, Armin; Lamptey, Jones; Yang, Jun-Pu; Feng, Qian; Wang, Mei-Jiao; Wang, Ying-Xiong; Ding, Yu-Bin

Emodin improves glucose metabolism and ovarian function in PCOS mice via the HMGB1/TLR4/NF-κB molecular pathway.

Otoo, Antonia; Czika, Armin; Lamptey, Jones; Yang, Jun-Pu; Feng, Qian; Wang, Mei-Jiao; Wang, Ying-Xiong; Ding, Yu-Bin.

Afiliação

Otoo A; Department of Obstetrics and Gynecology, Women and Children's Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Czika A; Department of Reproductive Biology, Joint International Research Laboratory of Reproduction and Development, School of Public Health, Chongqing Medical University, Chongqing, People's Republic of China.
Lamptey J; Department of Reproductive Biology, Joint International Research Laboratory of Reproduction and Development, School of Public Health, Chongqing Medical University, Chongqing, People's Republic of China.
Yang JP; Research and Development Institute, Faculty of Medicine, Transilvania University of Brasov, Brasov, Romania.
Feng Q; Department of Reproductive Biology, Joint International Research Laboratory of Reproduction and Development, School of Public Health, Chongqing Medical University, Chongqing, People's Republic of China.
Wang MJ; Department of Reproductive Biology, Joint International Research Laboratory of Reproduction and Development, School of Public Health, Chongqing Medical University, Chongqing, People's Republic of China.
Wang YX; Department of Gynecology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, People's Republic of China.
Ding YB; Department of Reproductive Biology, Joint International Research Laboratory of Reproduction and Development, School of Public Health, Chongqing Medical University, Chongqing, People's Republic of China.

Reproduction ; 166(5): 323-336, 2023 11 01.

Article em En | MEDLINE | ID: mdl-37651270

Assuntos

Emodina; Proteína HMGB1; Síndrome do Ovário Policístico; Animais; Feminino; Humanos; Camundongos; Emodina/farmacologia; Emodina/uso terapêutico; Glucose/metabolismo; Proteína HMGB1/genética; NF-kappa B; Obesidade/complicações; Síndrome do Ovário Policístico/metabolismo; Receptor 4 Toll-Like/genética

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Síndrome do Ovário Policístico / Emodina / Proteína HMGB1 Limite: Animals / Female / Humans Idioma: En Revista: Reproduction Assunto da revista: MEDICINA REPRODUTIVA Ano de publicação: 2023 Tipo de documento: Article

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