Direct Observation of Seeded Conformational Conversion of hIAPP <i>In Silico</i> Reveals the Mechanisms for Morphological Dependence and Asymmetry of Fibril Growth.

Huang, Gangtong; Tang, Huayuan; Liu, Yuying; Zhang, Chi; Ke, Pu Chun; Sun, Yunxiang; Ding, Feng

Direct Observation of Seeded Conformational Conversion of hIAPP In Silico Reveals the Mechanisms for Morphological Dependence and Asymmetry of Fibril Growth.

Huang, Gangtong; Tang, Huayuan; Liu, Yuying; Zhang, Chi; Ke, Pu Chun; Sun, Yunxiang; Ding, Feng.

Afiliação

Huang G; Department of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634, United States.
Tang H; Department of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634, United States.
Liu Y; School of Physical Science and Technology, Ningbo University, Ningbo 315211, China.
Zhang C; Department of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634, United States.
Ke PC; The Nanomedicine Center, The Great Bay Area National Institute for Nanotechnology Innovation, 136 Kaiyuan Avenue, Guangzhou 510700, China.
Sun Y; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia.
Ding F; Department of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634, United States.

J Chem Inf Model ; 63(18): 5863-5873, 2023 09 25.

Article em En | MEDLINE | ID: mdl-37651616

Assuntos

Amiloide; Humanos; Ligação de Hidrogênio; Conformação Molecular

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Amiloide Limite: Humans Idioma: En Revista: J Chem Inf Model Assunto da revista: INFORMATICA MEDICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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