cGAS-STING signaling pathway promotes hypoxia-induced renal fibrosis by regulating PFKFB3-mediated glycolysis.

Jiang, Anni; Liu, Jing; Wang, Yumei; Zhang, Chun

Jiang, Anni; Liu, Jing; Wang, Yumei; Zhang, Chun.

Afiliação

Jiang A; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Liu J; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Wang Y; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Zhang C; Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. Electronic address: drzhangchun@hust.edu.cn.

Free Radic Biol Med ; 208: 516-529, 2023 11 01.

Article em En | MEDLINE | ID: mdl-37714438

Assuntos

Nefropatias; Fosfofrutoquinase-2; Animais; Humanos; Masculino; Camundongos; Fibrose/metabolismo; Glicólise; Hipóxia/metabolismo; Nefropatias/metabolismo; Camundongos Endogâmicos C57BL; Nucleotidiltransferases/genética; Nucleotidiltransferases/metabolismo; Fosfofrutoquinase-2/genética; Fosfofrutoquinase-2/metabolismo; Transdução de Sinais

Palavras-chave

Chronic kidney disease; Glycolysis; PFKFB3; Renal fibrosis; STING

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Fosfofrutoquinase-2 / Nefropatias Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Free Radic Biol Med Assunto da revista: BIOQUIMICA / MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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