Exo-miR-1290-induced by COX-2 overexpression promotes cancer-associated fibroblasts activation and tumor progression by CUL3-Nrf2 pathway in lung adenocarcinoma.

Bai, Xiaoming; Shao, Jiaofang; Duan, Tinghong; Liu, Xue; Wang, Min; Li, Xuanya; You, Qiang; Zhang, Zhiyuan; Pan, Jinshun

Bai, Xiaoming; Shao, Jiaofang; Duan, Tinghong; Liu, Xue; Wang, Min; Li, Xuanya; You, Qiang; Zhang, Zhiyuan; Pan, Jinshun.

Afiliação

Bai X; Department of Pathology, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, P.R. China.
Shao J; Department of Bioinformatics, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, P.R. China.
Duan T; Department of Pathology, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, P.R. China.
Liu X; Department of Pathology, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, P.R. China.
Wang M; Department of Pathology, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, P.R. China.
Li X; Department of Pathology, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, P.R. China.
You Q; Department of Biotherapy, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, P.R. China.
Zhang Z; Department of Pathology, Nanjing Medical University, 101Longmian Avenue, Jiangning District, Nanjing, 211166, P.R. China. zzy@njmu.edu.cn.
Pan J; Department of Biotherapy, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, P.R. China. panjinshun@njmu.edu.cn.

Cell Commun Signal ; 21(1): 242, 2023 09 18.

Article em En | MEDLINE | ID: mdl-37723559

Assuntos

Adenocarcinoma de Pulmão; Fibroblastos Associados a Câncer; Neoplasias Pulmonares; Animais; Ciclo-Oxigenase 2; Fator 2 Relacionado a NF-E2; Neoplasias Pulmonares/genética

Palavras-chave

CAFs activation; COX-2; CUL3; Exo-miR-1290; LUAD; Nrf2

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pulmao Base de dados: MEDLINE Assunto principal: Fibroblastos Associados a Câncer / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Cell Commun Signal Ano de publicação: 2023 Tipo de documento: Article

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