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CHSY1 promotes CD8+ T cell exhaustion through activation of succinate metabolism pathway leading to colorectal cancer liver metastasis based on CRISPR/Cas9 screening.
Sun, Guangshun; Zhao, Siqi; Fan, Zhongguo; Wang, Yuliang; Liu, Hanyuan; Cao, Hengsong; Sun, Guoqiang; Huang, Tian; Cai, Hongzhou; Pan, Hong; Rong, Dawei; Gao, Yun; Tang, Weiwei.
Afiliação
  • Sun G; Hepatobiliary/Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Living Donor Transplantation, Chinese Academy of Medical Sciences, Nanjing, China.
  • Zhao S; Department of Breast Surgery, the First Affiliated Hospital With Nanjing Medical University, Nanjing, China.
  • Fan Z; Department of Surgery, the Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
  • Wang Y; Department of Cardiology Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
  • Liu H; School of Basic Medicine, Nanjing Medical University, Nanjing, China.
  • Cao H; Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
  • Sun G; Hepatobiliary/Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Living Donor Transplantation, Chinese Academy of Medical Sciences, Nanjing, China.
  • Huang T; Hepatobiliary/Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Living Donor Transplantation, Chinese Academy of Medical Sciences, Nanjing, China.
  • Cai H; Hepatobiliary/Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Living Donor Transplantation, Chinese Academy of Medical Sciences, Nanjing, China.
  • Pan H; Department of Urology, Jiangsu Cancer Hospital &The Affiliated Cancer Hospital of Nanjing Medical University& Jiangsu Institute of Cancer Research, Nanjing, China. caihongzhou@njmu.edu.cn.
  • Rong D; Department of Breast Surgery, the First Affiliated Hospital With Nanjing Medical University, Nanjing, China. pamghong@163.com.
  • Gao Y; Hepatobiliary/Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Living Donor Transplantation, Chinese Academy of Medical Sciences, Nanjing, China. rongdw9@126.com.
  • Tang W; Hepatobiliary/Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Living Donor Transplantation, Chinese Academy of Medical Sciences, Nanjing, China. gaoyunjs@sina.com.
J Exp Clin Cancer Res ; 42(1): 248, 2023 Sep 25.
Article em En | MEDLINE | ID: mdl-37749638
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Colon_e_reto Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / N-Acetilgalactosaminiltransferases / Artemisininas / Neoplasias Hepáticas Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Colon_e_reto Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / N-Acetilgalactosaminiltransferases / Artemisininas / Neoplasias Hepáticas Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China