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Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies.
Chong, Stephen Jun Fei; Zhu, Fen; Dashevsky, Olga; Mizuno, Rin; Lai, Jolin Xh; Hackett, Liam; Ryan, Christine E; Collins, Mary C; Iorgulescu, J Bryan; Guièze, Romain; Penailillo, Johany; Carrasco, Ruben; Hwang, Yeonjoo C; Muñoz, Denise P; Bouhaddou, Mehdi; Lim, Yaw Chyn; Wu, Catherine J; Allan, John N; Furman, Richard R; Goh, Boon Cher; Pervaiz, Shazib; Coppé, Jean-Philippe; Mitsiades, Constantine S; Davids, Matthew S.
Afiliação
  • Chong SJF; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Zhu F; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Dashevsky O; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Mizuno R; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Lai JX; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Hackett L; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Ryan CE; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Collins MC; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Iorgulescu JB; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Guièze R; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Penailillo J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Carrasco R; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Hwang YC; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Muñoz DP; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Bouhaddou M; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Lim YC; Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, California, USA.
  • Wu CJ; Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, California, USA.
  • Allan JN; Department of Microbiology, Immunology and Molecular Genetics, UCLA, Los Angeles, California, USA.
  • Furman RR; Cancer Science Institute, National University of Singapore, Singapore.
  • Goh BC; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Pervaiz S; Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York, USA.
  • Coppé JP; Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York, USA.
  • Mitsiades CS; Cancer Science Institute, National University of Singapore, Singapore.
  • Davids MS; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
J Clin Invest ; 133(22)2023 11 15.
Article em En | MEDLINE | ID: mdl-37751299

Texto completo: 1 Coleções: 01-internacional Temas: Cuidados_paliativos / Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Linfoma Difuso de Grandes Células B / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Temas: Cuidados_paliativos / Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Linfoma Difuso de Grandes Células B / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos