Non-Structural Protein-W61 as a Novel Target in Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV): An In-Vitro and In-Silico Study on Protein-Protein Interactions with Nucleoprotein and Viral Replication.

Park, Ji-Young; Sivasankar, Chandran; Kirthika, Perumalraja; Prabhu, Dhamodharan; Lee, John Hwa

Park, Ji-Young; Sivasankar, Chandran; Kirthika, Perumalraja; Prabhu, Dhamodharan; Lee, John Hwa.

Afiliação

Park JY; Department of Veterinary Public Health, College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Sivasankar C; Department of Veterinary Public Health, College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Kirthika P; Department of Veterinary Public Health, College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Prabhu D; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Lee JH; Centre for Drug Discovery, Karpagam Academy of Higher Education, Coimbatore 641021, India.

Viruses ; 15(9)2023 09 20.

Article em En | MEDLINE | ID: mdl-37766369

Assuntos

Infecções por Bunyaviridae; Phlebovirus; Febre Grave com Síndrome de Trombocitopenia; Humanos; Nucleoproteínas/genética; Nucleoproteínas/metabolismo; Células HeLa; Transdução de Sinais; Simulação de Acoplamento Molecular; Phlebovirus/genética; Replicação Viral; Serina/metabolismo; Proteínas não Estruturais Virais/genética; Proteínas não Estruturais Virais/metabolismo

Palavras-chave

SFTSV; in-vitro and in-silico analysis; protein-protein interaction; viral protein

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Phlebovirus / Infecções por Bunyaviridae / Febre Grave com Síndrome de Trombocitopenia Limite: Humans Idioma: En Revista: Viruses Ano de publicação: 2023 Tipo de documento: Article

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