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Evaluating the Efficacy of Platelet-Rich Fibrin Matrix versus Subepithelial Connective Tissue Grafts in Dental Root Coverage: A Comparative Study Using Modified Ruben's Technique.
Louis, Justina P; Crena, Jasmine M; Prakash, P S G; Subramanian, Sangeetha; Victor, Dhayanand John; Madapusi Balaji, Thodur; Zidane, Bassam; Al-Ahmari, Manea Musa Musleh; H Albar, Nassreen; Musleh Alahmari, Manea Musa; F Halawani, Ibrahim; Alzahrani, Khalid J; F Halawani, Abdullah; Patil, Shankargouda.
Afiliação
  • Louis JP; Department of Periodontics, SRM Dental College, Ramapuram, Chennai, India.
  • Crena JM; Department of Periodontics, SRM Dental College, Chennai, India.
  • Prakash PSG; Department of Periodontics, SRM Dental College, Chennai, India.
  • Subramanian S; Department of Periodontics, SRM Dental College, Chennai, India.
  • Victor DJ; Department of Periodontics, SRM Dental College, Chennai, India.
  • Madapusi Balaji T; Department of Dentistry, Bharathiraja Hospital, Chennai, India.
  • Zidane B; Department of Restorative Dentistry, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
  • Al-Ahmari MMM; Department of Periodontics and Community Medical Science, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
  • H Albar N; Division of Operative Dentistry, Department of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
  • Musleh Alahmari MM; Department of Periodontics and Community Medical Science, King Khalid University, Abha, Saudi Arabia.
  • F Halawani I; Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.
  • Alzahrani KJ; Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.
  • F Halawani A; Department of Biochemistry, King Faisal Hospital, Ministry of Health, Makkah, Saudi Arabia.
  • Patil S; College of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT, USA.
Med Sci Monit ; 29: e941473, 2023 Oct 03.
Article em En | MEDLINE | ID: mdl-37786246
ABSTRACT
BACKGROUND Dental root coverage, crucial in managing gingival recessions, traditionally utilizes subepithelial connective tissue grafts. However, this approach has limitations such as donor site morbidity and graft availability. Recent studies have introduced platelet-rich fibrin (PRF) as an alternative, leveraging its regenerative potential and growth factors. Despite the promise, comparative assessments between PRF and conventional grafts remain limited. This research probes whether PRF, when used beneath a modified Ruben's mixed flap, could provide comparable or superior dental root coverage than a subepithelial connective tissue graft. MATERIAL AND METHODS We enrolled 30 patients exhibiting Miller's class I and II recession in this comparative case series. Patients were randomly assigned to receive either a connective tissue graft (15 patients) or a PRF matrix (15 patients), both covered by a modified Ruben's mixed flap. RESULTS Clinical parameters, including full mouth plaque scores, bleeding scores, probing sulcus depth, clinical attachment level, gingival position assessment, width, and thickness of attached gingiva, were assessed in both the control and test groups at baseline, 6 months, and 12 months post-surgery. Significant differences were observed at all intervals.At the 12-month mark, the control group (connective tissue graft) achieved 91% complete root coverage, while the test group (PRF matrix) achieved 86%. However, this difference was not statistically significant. CONCLUSIONS The study outcomes suggest comparable gains in root coverage and attached gingiva between the connective tissue graft and PRF matrix groups. Thus, the results support our hypothesis that a subepithelial PRF matrix can serve as a viable alternative to a subepithelial connective tissue graft for treating dental root coverage.
Assuntos

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Fibrina Rica em Plaquetas / Retração Gengival Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Med Sci Monit Assunto da revista: MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Fibrina Rica em Plaquetas / Retração Gengival Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Med Sci Monit Assunto da revista: MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia