Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box<sup>FBXO11</sup> -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.

Zhang, Hao; Xia, Peng; Yang, Zhangshuo; Liu, Jie; Zhu, Yimin; Huang, Zan; Zhang, Zhonglin; Yuan, Yufeng

Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box^FBXO11 -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.

Zhang, Hao; Xia, Peng; Yang, Zhangshuo; Liu, Jie; Zhu, Yimin; Huang, Zan; Zhang, Zhonglin; Yuan, Yufeng.

Afiliação

Zhang H; Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xia P; Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Wuhan, China.
Yang Z; Department of Organ Transplantation, Qilu Hospital of Shandong University, Jinan, China.
Liu J; Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhu Y; Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Wuhan, China.
Huang Z; Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhang Z; Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Wuhan, China.
Yuan Y; Department of Breast Surgery, Affiliated Hospital of Hebei University, Baoding, China.

Clin Transl Med ; 13(10): e1443, 2023 10.

Article em En | MEDLINE | ID: mdl-37837399

Assuntos

Carcinoma Hepatocelular; Proteínas F-Box; Neoplasias Hepáticas; Animais; Camundongos; Humanos; Proteínas Culina/química; Proteínas Culina/genética; Proteínas Culina/metabolismo; Carcinoma Hepatocelular/genética; Proteínas Ligases SKP Culina F-Box/genética; Proteínas Ligases SKP Culina F-Box/metabolismo; Metabolismo dos Lipídeos/genética; Neoplasias Hepáticas/genética; Ubiquitinação/genética; Ribonucleoproteínas Nucleares Heterogêneas/genética; Ribonucleoproteínas Nucleares Heterogêneas/metabolismo; Lipídeos; Proteínas Quinases Associadas a Fase S/genética; Proteínas Quinases Associadas a Fase S/metabolismo; Proteína-Arginina N-Metiltransferases/metabolismo; Proteínas F-Box/metabolismo

Palavras-chave

SCF complex; adeno-associated virus; hepatocellular carcinoma; lipid metabolism reprogramming; ubiquitination

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Proteínas F-Box / Neoplasias Hepáticas Limite: Animals / Humans Idioma: En Revista: Clin Transl Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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