Role of CD44 expressed in renal tubules during maladaptive repair in renal fibrogenesis in an allopurinol-induced rat model of chronic kidney disease.

Matsushita, Kohei; Toyoda, Takeshi; Akane, Hirotoshi; Morikawa, Tomomi; Ogawa, Kumiko

Matsushita, Kohei; Toyoda, Takeshi; Akane, Hirotoshi; Morikawa, Tomomi; Ogawa, Kumiko.

Afiliação

Matsushita K; Division of Pathology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.
Toyoda T; Division of Pathology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.
Akane H; Division of Pathology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.
Morikawa T; Division of Pathology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.
Ogawa K; Division of Pathology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.

J Appl Toxicol ; 44(3): 455-469, 2024 Mar.

Article em En | MEDLINE | ID: mdl-37876353

Assuntos

Fibronectinas; Insuficiência Renal Crônica; Animais; Ratos; Alopurinol; Células Epiteliais/metabolismo; Fibronectinas/metabolismo; Fibrose; Receptores de Hialuronatos/metabolismo; Rim; Túbulos Renais/patologia; Insuficiência Renal Crônica/induzido quimicamente; Insuficiência Renal Crônica/genética; Insuficiência Renal Crônica/metabolismo

Palavras-chave

CD44; biomarker; chronic kidney disease; drug-induced kidney injury; maladaptive repair; partial epithelial-mesenchymal transition

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Fibronectinas / Insuficiência Renal Crônica Limite: Animals Idioma: En Revista: J Appl Toxicol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão

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