Targeting androgen receptor (AR) with a synthetic peptide increases apoptosis in triple negative breast cancer and AR-expressing prostate cancer cell lines.

Jamshidi, Mazdak; Keshavarzi, Fatemeh; Amini, Sabrieh; Laher, Ismail; Gheysarzadeh, Ali; Davari, Kambiz

Jamshidi, Mazdak; Keshavarzi, Fatemeh; Amini, Sabrieh; Laher, Ismail; Gheysarzadeh, Ali; Davari, Kambiz.

Afiliação

Jamshidi M; Department of Biology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.
Keshavarzi F; Department of Biology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.
Amini S; Department of Biology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.
Laher I; Department of Anesthesiology, Pharmacology and Therapeutics, The University of British Columbia, Vancouver, British Columbia, Canada.
Gheysarzadeh A; Department of Clinical Biochemistry, Ilam University of Medical Sciences, Ilam, Iran.
Davari K; Department of Biology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.

Cancer Rep (Hoboken) ; 7(1): e1922, 2024 01.

Article em En | MEDLINE | ID: mdl-37903548

Assuntos

Neoplasias da Próstata; Neoplasias de Mama Triplo Negativas; Masculino; Humanos; Receptores Androgênicos/metabolismo; Caspase 3; Proteína X Associada a bcl-2; Di-Hidrotestosterona/farmacologia; Neoplasias da Próstata/tratamento farmacológico; Neoplasias da Próstata/metabolismo; Apoptose; Linhagem Celular Tumoral; Proteínas Proto-Oncogênicas c-bcl-2

Palavras-chave

androgen receptor; anticancer peptide; apoptosis; breast cancer; dihydrotestosterone (DHT)

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Prostata Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Neoplasias de Mama Triplo Negativas Limite: Humans / Male Idioma: En Revista: Cancer Rep (Hoboken) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Irã

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