Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury.

Wen, Yumeng; Su, Emily; Xu, Leyuan; Menez, Steven; Moledina, Dennis G; Obeid, Wassim; Palevsky, Paul M; Mansour, Sherry G; Devarajan, Prasad; Cantley, Lloyd G; Cahan, Patrick; Parikh, Chirag R

Wen, Yumeng; Su, Emily; Xu, Leyuan; Menez, Steven; Moledina, Dennis G; Obeid, Wassim; Palevsky, Paul M; Mansour, Sherry G; Devarajan, Prasad; Cantley, Lloyd G; Cahan, Patrick; Parikh, Chirag R.

Afiliação

Wen Y; Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Su E; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Xu L; Section of Nephrology, Department of Medicine, Yale School of Medicine, New Haven, CT 06504, USA.
Menez S; Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Moledina DG; Section of Nephrology, Department of Medicine, Yale School of Medicine, New Haven, CT 06504, USA.
Obeid W; Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Palevsky PM; Renal-Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Mansour SG; Kidney Medicine Section, Medical Service, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA.
Devarajan P; Section of Nephrology, Department of Medicine, Yale School of Medicine, New Haven, CT 06504, USA.
Cantley LG; Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Cahan P; Section of Nephrology, Department of Medicine, Yale School of Medicine, New Haven, CT 06504, USA.
Parikh CR; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Sci Transl Med ; 15(726): eade7287, 2023 12 13.

Article em En | MEDLINE | ID: mdl-38091407

Assuntos

Injúria Renal Aguda; Traumatismo por Reperfusão; Camundongos; Adulto; Animais; Humanos; Proteoma/metabolismo; Transcriptoma/genética; Rim/metabolismo; Túbulos Renais Proximais; Injúria Renal Aguda/genética; Traumatismo por Reperfusão/metabolismo; Modelos Animais de Doenças

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Injúria Renal Aguda Limite: Adult / Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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