ALDOA coordinates PDE3A through the ß-catenin/ID3 axis to stimulate cancer metastasis and M2 polarization in lung cancer with EGFR mutations.

Yeh, Chia-Ying; Cai, Huei Yu; Kuo, Han-His; Lin, You-Yu; He, Zhao-Jing; Cheng, Hsiao-Chen; Yang, Chih-Jen; Huang, Chi-Ying F; Chang, Yu-Chan

Yeh, Chia-Ying; Cai, Huei Yu; Kuo, Han-His; Lin, You-Yu; He, Zhao-Jing; Cheng, Hsiao-Chen; Yang, Chih-Jen; Huang, Chi-Ying F; Chang, Yu-Chan.

Afiliação

Yeh CY; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Cai HY; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Kuo HH; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Lin YY; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
He ZJ; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Cheng HC; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Yang CJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; School of Post-Baccalaureate Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Huang CF; Institute of Biopharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chang YC; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan. Electronic address: yuchanchang@nycu.edu.tw.

Biochem Biophys Res Commun ; 696: 149489, 2024 Feb 12.

Article em En | MEDLINE | ID: mdl-38244313

Assuntos

Neoplasias Pulmonares; Humanos; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patologia; Frutose-Bifosfato Aldolase/genética; beta Catenina/genética; beta Catenina/metabolismo; Transdução de Sinais/genética; Nucleotídeo Cíclico Fosfodiesterase do Tipo 3/genética; Nucleotídeo Cíclico Fosfodiesterase do Tipo 3/metabolismo; Linhagem Celular Tumoral; Mutação; Receptores ErbB/genética; Receptores ErbB/metabolismo; Proteínas de Neoplasias/metabolismo; Proteínas Inibidoras de Diferenciação/genética

Palavras-chave

ALDOA; EGFR mutant; Lung cancer; PDE3; Trequinsin

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pulmao Base de dados: MEDLINE Assunto principal: Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Taiwan

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