Parecoxib sodium attenuates acute lung injury following burns by regulating M1/M2 macrophage polarization through the TLR4/NF-&#954;B pathway.

Huang, Dongxiao; Zhang, Zhongjun; Jian, Jinjin; Jiang, Xuliang; Gao, Jie; Yang, Minlie; Ding, Xian

Parecoxib sodium attenuates acute lung injury following burns by regulating M1/M2 macrophage polarization through the TLR4/NF-κB pathway.

Huang, Dongxiao; Zhang, Zhongjun; Jian, Jinjin; Jiang, Xuliang; Gao, Jie; Yang, Minlie; Ding, Xian.

Afiliação

Huang D; Department of Anaesthesiology, Jiangnan University Medical Center, Wuxi No.2 People's Hospital, Wuxi, 214002, China.
Zhang Z; Department of Anaesthesiology, The Affiliated Hospital of Jiangnan University, No.1000 Hefeng Road, Wuxi, 214122, China.
Jian J; Department of Anaesthesiology, The Affiliated Hospital of Jiangnan University, No.1000 Hefeng Road, Wuxi, 214122, China.
Jiang X; Department of Anesthesiology. Fudan University Shanghai Cancer Center, Shanghai, 200030, China.
Gao J; Department of Anaesthesiology, The Affiliated Hospital of Jiangnan University, No.1000 Hefeng Road, Wuxi, 214122, China.
Yang M; Burn and Palstic Surgery, The Affiliated Hospital of Jiangnan University, No.1000 Hefeng Road, Wuxi, 214122, China. Electronic address: minl_yang@163.com.
Ding X; Department of Anaesthesiology, The Affiliated Hospital of Jiangnan University, No.1000 Hefeng Road, Wuxi, 214122, China. Electronic address: 9862018025@jiangnan.edu.cn.

Eur J Pharmacol ; 968: 176407, 2024 Apr 05.

Article em En | MEDLINE | ID: mdl-38365106

Assuntos

Lesão Pulmonar Aguda; Queimaduras; Isoxazóis; Camundongos; Animais; NF-kappa B/metabolismo; Receptor 4 Toll-Like/metabolismo; Lesão Pulmonar Aguda/etiologia; Lesão Pulmonar Aguda/induzido quimicamente; Macrófagos; Pulmão; Queimaduras/complicações; Queimaduras/tratamento farmacológico; Queimaduras/metabolismo; Lipopolissacarídeos/farmacologia

Palavras-chave

Acute lung injury (ALI); Macrophage polarization; NF-κB; Parecoxib sodium; TLR4

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Queimaduras / Lesão Pulmonar Aguda / Isoxazóis Limite: Animals Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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