A Fe(III) intercalated clay nanoplatform for combined chemo/chemodynamic therapy.

Chen, Ying; Zhai, Jing; Wei, Shiqi; Tang, Aidong; Yang, Huaming

Chen, Ying; Zhai, Jing; Wei, Shiqi; Tang, Aidong; Yang, Huaming.

Afiliação

Chen Y; Engineering Research Center of Nano-Geomaterials of Ministry of Education, China University of Geosciences, Wuhan 430074, China. tangaidong@cug.edu.cn.
Zhai J; Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China.
Wei S; Laboratory of Advanced Mineral Materials, China University of Geosciences, Wuhan 430074, China.
Tang A; Engineering Research Center of Nano-Geomaterials of Ministry of Education, China University of Geosciences, Wuhan 430074, China. tangaidong@cug.edu.cn.
Yang H; Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China.

Chem Commun (Camb) ; 60(26): 3535-3538, 2024 Mar 26.

Article em En | MEDLINE | ID: mdl-38450703

ABSTRACT

ABSTRACT

A Fe(III) intercalated montmorillonite nanoplatform (Fe-MMT) was engineered for doxorubicin (DOX) loading. The constructed Fe-MMT/DOX nanoplatform could not only improve the production of H2O2 to enhance chemodynamic therapy but interfere with DNA damage repair to amplify the efficacy of DOX, proving an ideal combination of chemotherapy and chemodynamic therapy.

Assuntos

Compostos Férricos; Neoplasias; Humanos; Argila; Peróxido de Hidrogênio; Doxorrubicina/farmacologia; Linhagem Celular Tumoral

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Compostos Férricos / Neoplasias Limite: Humans Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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