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Biopolymeric Innovations in Ophthalmic Surgery: Enhancing Devices and Drug Delivery Systems.
Wu, Kevin Y; Khan, Sameer; Liao, Zhuoying; Marchand, Michael; Tran, Simon D.
Afiliação
  • Wu KY; Department of Surgery, Division of Ophthalmology, University of Sherbrooke, Sherbrook, QC J1G 2E8, Canada.
  • Khan S; Department of Biology, Carleton University, Ottawa, ON K1S 5B6, Canada.
  • Liao Z; Department of Biology, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Marchand M; Department of Surgery, Division of Ophthalmology, University of Sherbrooke, Sherbrook, QC J1G 2E8, Canada.
  • Tran SD; Faculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, QC H3A 1G1, Canada.
Polymers (Basel) ; 16(12)2024 Jun 16.
Article em En | MEDLINE | ID: mdl-38932068
ABSTRACT
The interface between material science and ophthalmic medicine is witnessing significant advances with the introduction of biopolymers in medical device fabrication. This review discusses the impact of biopolymers on the development of ophthalmic devices, such as intraocular lenses, stents, and various prosthetics. Biopolymers are emerging as superior alternatives due to their biocompatibility, mechanical robustness, and biodegradability, presenting an advance over traditional materials with respect to patient comfort and environmental considerations. We explore the spectrum of biopolymers used in ophthalmic devices and evaluate their physical properties, compatibility with biological tissues, and clinical performances. Specific applications in oculoplastic and orbital surgeries, hydrogel applications in ocular therapeutics, and polymeric drug delivery systems for a range of ophthalmic conditions were reviewed. We also anticipate future directions and identify challenges in the field, advocating for a collaborative approach between material science and ophthalmic practice to foster innovative, patient-focused treatments. This synthesis aims to reinforce the potential of biopolymers to improve ophthalmic device technology and enhance clinical outcomes.
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Idioma: En Revista: Polymers (Basel) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Canadá

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Idioma: En Revista: Polymers (Basel) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Canadá