Joint association of weight-adjusted-waist index and physical activity with insulin resistance in adolescents: a cross-sectional study.
BMC Endocr Disord
; 24(1): 100, 2024 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-38951821
ABSTRACT
BACKGROUND:
The weight-adjusted waist index (WWI) is a recently developed obesity metric, and the aim of this study was to investigate the relationship between physical activity (PA) and WWI and the homeostasis model assessment of insulin resistance (HOMA-IR) in adolescents, as well as the joint association of HOMA-IR.METHODS:
This study was based on the National Health and Nutrition Survey conducted between 2013 and 2016 and included 1024 adolescents whose median age was 15.4. Multivariate linear regression was used to examine the associations between HOMA-IR and PA and WWI. Using generalized additive models, a potential nonlinear link between WWI and HOMA-IR was evaluated. Subgroup analysis was also carried out.RESULTS:
The fully adjusted model revealed a positive association (ß 0.48, 95% CI 0.43, 0.53) between the WWI and HOMA-IR. The HOMA-IR was lower in physically active (ß -0.16, 95% CI -0.26, -0.05) participants versus inactive participants. Participants who had higher WWI and were not physically active (ß 0.69; 95% CI 0.56, 0.82) had the highest levels of HOMA-IR compared to participants who had lower WWI and were physically active. Subgroup analysis revealed that these correlations were similar in males and females.CONCLUSION:
Our results demonstrated that higher WWI and PA were associated with a lower HOMA-IR and that WWI and PA had a combined association with HOMA-IR. The findings of this study are informative for the preventing insulin resistance in adolescents.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Alimentacao
Base de dados:
MEDLINE
Assunto principal:
Resistência à Insulina
/
Exercício Físico
Limite:
Adolescent
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
BMC Endocr Disord
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China