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Nanoparticles and Their Applications in Lipid Signaling.
Ashin, Zeinab Fotouhi; Yacoub, Ahmed S; Saady, Marwa; Thompson, Sophia E; Awad, Kamal; Aswath, Pranesh; Brotto, Marco; Varanasi, Venu.
Afiliação
  • Ashin ZF; Department of Materials Science and Engineering, The University of Texas at Arlington, Arlington, TX, USA.
  • Yacoub AS; Bone Muscle Research Center, The University of Texas at Arlington, Arlington, TX, USA.
  • Saady M; Bone Muscle Research Center, The University of Texas at Arlington, Arlington, TX, USA.
  • Thompson SE; Department of Kinesiology, College of Nursing and Health Innovation, The University of Texas at Arlington, Arlington, TX, USA.
  • Awad K; Chemistry Department, School of Sciences & Engineering, The American University in Cairo, Cairo, Egypt.
  • Aswath P; Bone Muscle Research Center, The University of Texas at Arlington, Arlington, TX, USA.
  • Brotto M; Bone Muscle Research Center, The University of Texas at Arlington, Arlington, TX, USA.
  • Varanasi V; Department of Materials Science and Engineering, The University of Texas at Arlington, Arlington, TX, USA.
Methods Mol Biol ; 2816: 41-52, 2024.
Article em En | MEDLINE | ID: mdl-38977587
ABSTRACT
This chapter provides an overview of the diverse range of applications associated with nanoparticles. The application of nanoparticles in the medical field has garnered considerable attention due to their unique properties and versatile compositions. They have shown promise in the treatment of cancer, fungal and viral infections, and pain management. These systems provide numerous benefits, such as increased drug stability, improved bioavailability, and targeted delivery to specific tissues or cells. The objective of this chapter is to provide a brief analysis of the differences between nanoparticles and lipid particles, focusing particularly on the importance of nanoparticle size and composition in their interactions with lipids. Additionally, the applications of nanoparticles in lipid signaling will be discussed, considering the vital roles lipids play in cellular signaling pathways. Nanoparticles have shown immense potential in the regulation and control of medical pathways. In this case, we will focus on the manufacture of liposomes, a type of nanoparticle composed of lipids. The reason behind the extensive investigation into liposomes as drug delivery vehicles is their remarkable biocompatibility and adaptability. This section will provide insights into the methods and techniques employed for liposome formulation.
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Nanopartículas / Lipídeos / Lipossomos Limite: Animals / Humans Idioma: En Revista: Methods Mol Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Nanopartículas / Lipídeos / Lipossomos Limite: Animals / Humans Idioma: En Revista: Methods Mol Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos