[Changes in lymphocyte cytochemical markers in radiation-exposed patients under mountain conditions]. / Izmenenie tsitokhimicheskikh markerov limfotsitov u postradiatsionnykh bol'nykh v usloviiakh gor.

ABSTRACT

It is shown that 24-day rehabilitation in the mountains reduced general sensitization in subjects exposed to radiation after the Chernobyl accident. The assessment of lymphocyte population and functional activity (lysosomal, mitochondrial, mitotic) by their markers (acid phosphatase, succinate dehydrogenase, DNA) indicated lowering of B-lymphocyte count, T-killers, increased count of o-lymphocytes, DNA in all lymphocyte populations, a rise in the activity of SDG and acid phosphatase. Subjects from the Chernobyl rescue teams living in high altitudes for 3-15 years after the accident had low T-lymphocyte but high o-lymphocyte counts, stable SDG, enhanced activity of acid phosphates in T-killers. The fact of lymphocyte populations increase, stimulation of their activity observed in the end of the radiation-exposed subjects, rehabilitation gives grounds for further investigations of beneficial effect of mountain climate on irradiated body, of relevant indications and contraindications.