[Comparison of leukocyte filters for erythrocyte concentration]. / Vergleich von Leukozytenfiltern für Erythrozytenkonzentrate.

ABSTRACT

UNLABELLED We compared the following leukocyte filter blood systems (BBS) Biotrans Bio R01 Plus, Diamed Sepacell RS-200, Pall BPF4 (log 4 filters) and Biotrans Bio R01 (log 3 filter). We evaluated the leukocyte removal, handling, the increase of free hemoglobin and the loss of red blood cells (RBC) by filtration. A total of 54 buffy-coat-reduced RBCs were suspended in 200 ml PAGGS-M, stored at +4 degrees C for 24 h and filtered subsequently. Samples were taken before storage, immediately before and after filtration to measure total and free Hb and the white blood cell (WBC) contamination. RESULTS: (1) All log 4 filters showed a comparable reduction of the WBC content per RBC concentrate. (2) Differences were observed in total filtration time and loss of RBCs Biotrans Bio R01 Plus and Pall BPF4 yielded significantly better results than Diamed Sepacell RS-200. (3) The log 3 filter did not meet the criteria of < 5 x 10(6) WBCs per filtered unit of RBCs (as recommended by the Council of Europe).