Mapping of 22 new ESTs around a tumor suppressor gene and a senescence gene at 6q16-->q21.
Cytogenet Cell Genet
; 79(1-2): 97-100, 1997.
Article
em En
| MEDLINE
| ID: mdl-9533021
ABSTRACT
Twenty two expressed sequence tags (ESTs) have been mapped at the border of 6q16-->q21 and at the proximal end of 6q21, a candidate for two tumor suppressor genes and a senescence gene. Use of a translocation and deletion hybrid panel together with a 4-Mb YAC contig allowed us to precisely define the position of the ESTs. Thirteen ESTs were placed within the 4-Mb interval at the proximal portion of 6q21 using a restriction map of the YAC contig, seven ESTs span a 2-Mb region on the 6q16-->q21 border, and two are distal to the contig. Refinement of the localization of these ESTs will provide substantial assistance in identifying new genes within the region 6q16-->q21.
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Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Translocação Genética
/
Cromossomos Humanos Par 6
/
Envelhecimento
/
Genes Supressores de Tumor
/
Mapeamento Cromossômico
Limite:
Humans
Idioma:
En
Revista:
Cytogenet Cell Genet
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Itália