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[Certain biochemical features of leukocytes in blast crisis of chronic myelogenous leukemia]. / Nekotorye biokhimicheskie osobennosti leikotsitov pri blastnom krize khronicheskogo mieloleikoza.
Kharchenko, M F; Rybakova, L P; Filanovskaia, L I; Saltykova, L B; Bitiukova, E S; Shcherbakova, E G; Rukavitsyn, O A; Bessmel'tsev, S S; Abdulkadyrov, K M; Blinov, M M.
Afiliação
  • Kharchenko MF; Russian Research Institute of Hematology and Transfusiology, St. Petersburg.
Vopr Med Khim ; 44(3): 274-80, 1998.
Article em Ru | MEDLINE | ID: mdl-9703628
The content of nuclear high mobility group (HMG) proteins, activities of ornithine decarboxylase (ODC), adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) and also glycosaminoglycan (GAG) content and composition were studied in leukocytes of patients with chronic myelogenous leukemia in the phase of blast crisis (BC CML). Myeloid and lymphoid cytochemical variants of BC CML differ by biochemical parameters. It is suggested, that the content of HMG-proteins, activities of ODC and PNP, and electrophoretic patterns of GAGs could be used in diagnostics of two main variants of BC CML.
Assuntos
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Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Leucemia Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Crise Blástica / Leucócitos Limite: Humans Idioma: Ru Revista: Vopr Med Khim Ano de publicação: 1998 Tipo de documento: Article
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Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Leucemia Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Crise Blástica / Leucócitos Limite: Humans Idioma: Ru Revista: Vopr Med Khim Ano de publicação: 1998 Tipo de documento: Article