Cost-Effectiveness Analysis of Varenicline Versus Currently Funded Smoking Cessation Strategies in Brazil.

OBJECTIVES: To assess the cost-effectiveness of varenicline in comparison to currently funded smoking cessation strategies in Brazil. METHODS: We modeled the lifetime direct costs and health-related quality of life of a hypothetical cohort of smokers with a single attempt to quit smoking using one of the following: (1) cognitive behavioral therapy (CBT) without any pharmacological intervention, (2) varenicline, (3) bupropion, (4) nicotine replacement therapy (NRT) with transdermal patch, (5) bupropion in combination with NRT transdermal patch, and (6) combined NRT (oral plus transdermal). All drug alternatives were considered with concomitant CBT. The analysis relied on a Markov model based on the Benefits of Smoking Cessation and Outcomes study and used different age and sex categories in the consideration of relative risks and incidence rates of the diseases included in the model. The analysis was conducted from the healthcare system perspective, and a 3% discounting rate for costs and outcomes was applied. Model parameter values were sourced from published literature. Probabilistic and deterministic sensitivity analyses assessed robustness. RESULTS: Among the smoking cessation alternatives available in Brazil, varenicline and combined NRT were estimated to have higher effectiveness; varenicline, however, was dominated due to its higher average cost. In the base-case analysis, combined NRT had an incremental gain of 0.25 quality-adjusted life-years (QALYs) in comparison to the second-best option (bupropion in combination with NRT transdermal patch) and an incremental cost-effectiveness ratio of R$2173.47/QALY ($595.45/QALY). CONCLUSIONS: Combination of oral and transdermal NRT (coupled with CBT) was the most effective smoking cessation option and was 100% cost-effective within a conservative willingness-to-pay threshold.

Dietary patterns, sociodemographic and behavioral characteristics among Brazilian adolescents. / Padrões alimentares, características sociodemográficas e comportamentais entre adolescentes brasileiros.

INTRODUCTION: Inadequate dietary patterns in childhood and adolescence are a major risk factor for the early onset of obesity and other chronic diseases. OBJECTIVES: To identify and to analyze dietary patterns among Brazilian adolescents. METHODS: Data from the Brazilian National School Health Survey (PeNSE) of 2015 were used (n = 10,926 adolescents). The identification and analyses of dietary patterns were calculated using principal component analysis and linear regression, respectively. RESULTS: Two dietary patterns were identified. The first one was characterized by the presence of markers of unhealthy eating, and the second one by markers of healthy eating. The adherence to the unhealthy pattern was positively associated with female adolescents, which mothers had completed, at least, the elementary school, residents in developed regions and urban areas, as well as those students who usually chose to skip breakfast, to not have meals with their parents/guardians, and who usually had meals while watching TV/studying, and at fast food restaurants. DISCUSSION: Analyses of the consumption of isolated food groups, which do not consider the diet in all its complexity, have been insufficient in explaining the main outcomes of the public health nutrition area. CONCLUSION: Our findings contributed to the identification of the most vulnerable population groups to unhealthy dietary patterns and to the understanding of the coexistence of different food habit determinants among adolescents.

INTRODUçÃO: Padrões inadequados de alimentação na infância e na adolescência são um dos principais fatores de risco para o aparecimento precoce da obesidade e de outras doenças crônicas. OBJETIVOS: Identificar e analisar os padrões alimentares entre os adolescentes brasileiros. MÉTODOS: Foram utilizados dados da Pesquisa Nacional de Saúde do Escolar de 2015 (n = 10.926 adolescentes). A identificação e a análise dos padrões alimentares foram realizadas por meio da análise de componentes principais e pela regressão linear, respectivamente. RESULTADOS: Dois padrões foram identificados: o primeiro, caracterizado por marcadores de uma alimentação não saudável; e o segundo, por marcadores de uma alimentação saudável. A adesão ao padrão não saudável esteve positivamente associada aos adolescentes do sexo feminino, que possuem mães com, ao menos, ensino fundamental completo, que residem em regiões mais desenvolvidas e em área urbana, bem como entre aqueles que possuem o hábito de não tomar café da manhã, não realizar as refeições com os pais/responsáveis, se alimentar enquanto estuda ou assiste TV e frequentar restaurantes fast-food. DISCUSSÃO: Análises do consumo de grupos alimentares isolados, que não consideram a dieta em toda a sua complexidade, têm se mostrado insuficientes na explicação dos principais desfechos da área de nutrição em saúde pública. CONCLUSÃO: Os achados contribuíram para a identificação de grupos populacionais mais vulneráveis ao padrão alimentar não saudável e para a compreensão da coexistência de diferentes determinantes ao hábito alimentar entre os adolescentes.

Nutritional status, body image, and their association with extreme weight control behaviors among Brazilian adolescents, National Adolescent Student Health Survey 2015. / Estado nutricional, imagem corporal e associação com comportamentos extremos para controle de peso em adolescentes brasileiros, Pesquisa Nacional de Saúde do Escolar de 2015.

INTRODUCTION: This study aimed to analyze the association between nutritional status, body image perception, and extreme weight control behaviors among adolescents. METHODS: This is an analytical cross-sectional study conducted in Brazil based on the National Adolescent Student Health Survey (Pesquisa Nacional de Saúde do Escolar - PeNSE) of 2015, with adolescents aged 13 to 17 years. Nutritional status and body image perception were the independent variables. The two dependent variables were vomiting or laxative use and use of medicines and other formulas for weight control in the 30 days prior to data collection. We used Poisson regression models for association, with demographic variables for control. RESULTS: 7.4% of adolescents (95%CI 6.7 - 8.2) reported vomiting or using laxatives, with no difference between genders. The prevalence of use of medicines and formulas was higher among boys (7.8%; 95%CI 6.6 - 8.9). The association between nutritional status and extreme behaviors was not significant. However, the prevalence of vomiting or laxative use for adolescents who considered themselves very fat was 2.3 (95%CI 1.1 - 4.7) times higher for boys and 5.3 (95%CI 3.3 - 8.6) times higher for girls, while the use of medicines and formulas was 4.0 (95%CI 2.3 - 7.1) times higher for girls who considered themselves very fat. CONCLUSION: Body image perception seems to have a greater influence on extreme behaviors than nutritional status. Strategies involving health services and schools have great potential to impact the self-esteem and health of students positively.

INTRODUÇÃO: Este estudo objetivou analisar a associação entre estado nutricional, percepção da imagem corporal e comportamentos extremos para controle de peso nos adolescentes. METODOLOGIA: Estudo transversal analítico, realizado no Brasil a partir da Pesquisa Nacional de Saúde do Escolar (PeNSE) de 2015, com adolescentes de 13 a 17 anos. Estado nutricional e percepção da imagem corporal foram as variáveis independentes. As dependentes foram vômito ou uso de laxantes e uso de remédios e outras fórmulas para controle de peso nos últimos 30 dias. Modelos de regressão de Poisson foram empregados para associação, com uso de variáveis demográficas para controle. RESULTADOS: 7,4% dos adolescentes (IC95% 6,7 - 8,2) relataram vômito ou uso de laxantes, sem diferença entre os sexos. A prevalência de uso de remédio e fórmulas foi maior entre meninos (7,8%; IC95% 6,6 - 8,9). A associação entre estado nutricional e comportamentos extremos não foi significativa; entretanto, a prevalência de vômito ou uso de laxantes foi 2,3 (IC95% 1,1 - 4,7) vezes maior em meninos e 5,3 (IC95% 3,3 - 8,6) vezes maior em meninas que se sentiam muito gordos(as), ao passo que uso de remédios e fórmulas foi 4,0 vezes (IC95% 2,3 - 7,1) maior em meninas que sentiam muito gordas. CONCLUSÃO: A percepção da imagem corporal parece ter maior influência na prática dos comportamentos extremos do que o estado nutricional. Estratégias envolvendo serviços de saúde e escolas têm grande potencialidade para ações que impactem positivamente na autoestima e na saúde dos estudantes.

Trends in violent situations experienced by Brazilian adolescents: National Adolescent Student Health Survey 2009, 2012, and 2015. / Tendências de situações de violência vivenciadas por adolescentes brasileiros: Pesquisa Nacional de Saúde do Escolar 2009, 2012 e 2015.

OBJECTIVE: To present trends found in the last three editions of the National Adolescent Student Health Survey (Pesquisa Nacional de Saúde do Escolar - PeNSE) on violent situations experienced by Brazilian students. METHODS: Time-series study with a focus on the Brazilian state capitals, using PeNSE databases of 2009, 2012, and 2015. The indicators evaluated were: missing classes due to insecurity in the home-school route or at school; involvement in a fight with firearm or melee weapon; and physical assault by an adult of the family. We estimated the prevalence of indicators according to the total number of adolescents, gender, school type, and capital. Trends in prevalence were estimated by linear regression, adjusted for age. RESULTS: We identified a trend in increasing prevalence, with statistical significance, for all selected violence indicators in the period from 2009 to 2015, in Brazilian state capitals. DISCUSSION: The most vulnerable groups were public schools students; male adolescents for involvement in fights with melee weapons or firearms; and female adolescents for physical assault by family members. CONCLUSION: PeNSE contributed to identifying the increase in the prevalence of violence experienced by adolescents, which alerts to the need of planning and implementing policies that help to prevent violence, and promote health and a culture of peace.

OBJETIVO: Apresentar as tendências encontradas nas três últimas edições da Pesquisa Nacional de Saúde do Escolar (PeNSE) sobre situações de violência vivenciadas por escolares brasileiros. METODOLOGIA: Estudo de séries temporais com recorte para as capitais brasileiras, utilizando as bases de dados da PeNSE de 2009, 2012 e 2015. Os indicadores avaliados foram: faltar às aulas por insegurança no trajeto casa-escola ou na escola; envolvimento em briga com arma de fogo ou arma branca; e agressão por adulto da família. Foram estimadas as prevalências dos indicadores para o total dos adolescentes, por sexo, tipo de escola e capitais. As tendências das prevalências foram estimadas por meio de regressão linear, ajustadas por idade. RESULTADOS: Identificou-se tendência de aumento das prevalências, com significância estatística, para todos os indicadores de violência selecionados no período de 2009 a 2015, nas capitais brasileiras. DISCUSSÃO: Os grupos mais vulneráveis foram escolares das escolas públicas; adolescentes do sexo masculino no caso do envolvimento em brigas com arma branca ou de fogo; e adolescentes do sexo feminino no caso de agressão física por familiar. CONCLUSÃO: A PeNSE contribuiu para identificar o aumento das prevalências de violências vividas pelos adolescentes, o que alerta para a necessidade de planejamento e implementação de políticas que contribuam para a prevenção de violência, promoção da saúde e da cultura de paz.

Profile and trend of risk factors for traffic accidents in schoolchildren in Brazilian capitals: PeNSE 2009, 2012 and 2015. / Perfil e tendência dos fatores de risco para acidentes de trânsito em escolares nas capitais brasileiras: PeNSE 2009, 2012 e 2015.

INTRODUCTION: Land transport accidents (LTA) are the second cause of death in schoolchildren aged 13 to 17 years. The study aims to describe the risk factors for LTA in schoolchildren from the National School Health Survey (PeNSE) of 2015 and to evaluate the trend of selected indicators in the last three editions of PeNSE. METHODOLOGY: A descriptive study on risk factors for LTA in 2015, with PeNSE data and time series trends analysis, with age-adjusted regression tests of the 2009, 2012 and 2015 editions, in Brazilian capitals. RESULTS: In 2015, 26.3% of ninth grade schoolchildren, mostly between 13 and 15 years of age, reported having been in a motor vehicle driven by someone who consumed alcohol and 32.4% had driven a motor vehicle; 30.7% of adolescents did not use seat belts in the back seat; and 16.8% of schoolchildren who ride motorcycles did not wear helmets. There was also a worsening of the indicators between 2009 and 2015, regarding driving a motor vehicle (1.0 percentage points) and having been driven by vehicle for consumption of alcoholic beverages (1.1 percentage points). DISCUSSION: The LTA occurrence results from the interaction between roads, vehicles and users, and has a strong correlation with behavior. CONCLUSIONS: The results show the need to invest in educational measures, associated with supervision, the improvement of road infrastructure, research and improvement of legislation. The monitoring of risk factors in schoolchildren substantially contributes to support intersectoral public policies interventions to reduce morbidity and mortality in traffic.

INTRODUÇÃO: Os acidentes de transporte terrestre (ATT) são a segunda causa de morte em escolares de 13 a 17 anos. O presente estudo visou descrever os fatores de risco para ATT em escolares da Pesquisa Nacional de Saúde do Escolar (PeNSE) de 2015 e avaliar a tendência de indicadores selecionados nas três últimas edições da PeNSE. METODOLOGIA: Estudo descritivo sobre fatores de risco para ATT no ano de 2015, com dados da PeNSE e análise de tendência das séries temporais, com testes de regressão ajustados por idade, das edições de 2009, 2012 e 2015, nas capitais brasileiras. RESULTADOS: Em 2015, 26,3% dos escolares do nono ano, na maioria entre 13 e 15 anos, relataram terem sido conduzidos em veículo motorizado dirigido por alguém que consumiu bebida alcoólica e 32,4% relataram terem dirigido veículo motorizado; 30,7% dos adolescentes não usaram cinto de segurança no banco de trás; e 16,8% dos escolares usuários de motocicleta não usaram capacetes. Observou-se ainda tendência de piora dos indicadores entre 2009 e 2015, referentes a dirigir veículo motorizado (1,0 pontos percentuais) e ter sido conduzido em veículo por alguém que consumiu bebida alcoólica (1,1 pontos percentuais). DISCUSSÃO: A ocorrência de ATT resulta da interação entre vias, veículos e usuários, tendo forte correlação com o comportamento. CONCLUSÕES: Os resultados apontam a necessidade de investir em medidas educativas, associadas a fiscalização, a melhoria das vias, pesquisas e aprimoramento da legislação. O monitoramento dos fatores de risco em escolares contribui substancialmente para apoiar intervenções das políticas públicas intersetoriais para a redução de morbimortalidade por trânsito.

Padrões alimentares, características sociodemográficas e comportamentais entre adolescentes brasileiros / Dietary patterns, sociodemographic and behavioral characteristics among Brazilian adolescents

RESUMO: Introdução: Padrões inadequados de alimentação na infância e na adolescência são um dos principais fatores de risco para o aparecimento precoce da obesidade e de outras doenças crônicas. Objetivos: Identificar e analisar os padrões alimentares entre os adolescentes brasileiros. Métodos: Foram utilizados dados da Pesquisa Nacional de Saúde do Escolar de 2015 (n = 10.926 adolescentes). A identificação e a análise dos padrões alimentares foram realizadas por meio da análise de componentes principais e pela regressão linear, respectivamente. Resultados: Dois padrões foram identificados: o primeiro, caracterizado por marcadores de uma alimentação não saudável; e o segundo, por marcadores de uma alimentação saudável. A adesão ao padrão não saudável esteve positivamente associada aos adolescentes do sexo feminino, que possuem mães com, ao menos, ensino fundamental completo, que residem em regiões mais desenvolvidas e em área urbana, bem como entre aqueles que possuem o hábito de não tomar café da manhã, não realizar as refeições com os pais/responsáveis, se alimentar enquanto estuda ou assiste TV e frequentar restaurantes fast-food. Discussão: Análises do consumo de grupos alimentares isolados, que não consideram a dieta em toda a sua complexidade, têm se mostrado insuficientes na explicação dos principais desfechos da área de nutrição em saúde pública. Conclusão: Os achados contribuíram para a identificação de grupos populacionais mais vulneráveis ao padrão alimentar não saudável e para a compreensão da coexistência de diferentes determinantes ao hábito alimentar entre os adolescentes.

ABSTRACT: Introduction: Inadequate dietary patterns in childhood and adolescence are a major risk factor for the early onset of obesity and other chronic diseases. Objectives: To identify and to analyze dietary patterns among Brazilian adolescents. Methods: Data from the Brazilian National School Health Survey (PeNSE) of 2015 were used (n = 10,926 adolescents). The identification and analyses of dietary patterns were calculated using principal component analysis and linear regression, respectively. Results: Two dietary patterns were identified. The first one was characterized by the presence of markers of unhealthy eating, and the second one by markers of healthy eating. The adherence to the unhealthy pattern was positively associated with female adolescents, which mothers had completed, at least, the elementary school, residents in developed regions and urban areas, as well as those students who usually chose to skip breakfast, to not have meals with their parents/guardians, and who usually had meals while watching TV/studying, and at fast food restaurants. Discussion: Analyses of the consumption of isolated food groups, which do not consider the diet in all its complexity, have been insufficient in explaining the main outcomes of the public health nutrition area. Conclusion: Our findings contributed to the identification of the most vulnerable population groups to unhealthy dietary patterns and to the understanding of the coexistence of different food habit determinants among adolescents.

Perfil e tendência dos fatores de risco para acidentes de trânsito em escolares nas capitais brasileiras: PeNSE 2009, 2012 e 2015 / Profile and trend of risk factors for traffic accidents in schoolchildren in Brazilian capitals: PeNSE 2009, 2012 and 2015

RESUMO: Introdução: Os acidentes de transporte terrestre (ATT) são a segunda causa de morte em escolares de 13 a 17 anos. O presente estudo visou descrever os fatores de risco para ATT em escolares da Pesquisa Nacional de Saúde do Escolar (PeNSE) de 2015 e avaliar a tendência de indicadores selecionados nas três últimas edições da PeNSE. Metodologia: Estudo descritivo sobre fatores de risco para ATT no ano de 2015, com dados da PeNSE e análise de tendência das séries temporais, com testes de regressão ajustados por idade, das edições de 2009, 2012 e 2015, nas capitais brasileiras. Resultados: Em 2015, 26,3% dos escolares do nono ano, na maioria entre 13 e 15 anos, relataram terem sido conduzidos em veículo motorizado dirigido por alguém que consumiu bebida alcoólica e 32,4% relataram terem dirigido veículo motorizado; 30,7% dos adolescentes não usaram cinto de segurança no banco de trás; e 16,8% dos escolares usuários de motocicleta não usaram capacetes. Observou-se ainda tendência de piora dos indicadores entre 2009 e 2015, referentes a dirigir veículo motorizado (1,0 pontos percentuais) e ter sido conduzido em veículo por alguém que consumiu bebida alcoólica (1,1 pontos percentuais). Discussão: A ocorrência de ATT resulta da interação entre vias, veículos e usuários, tendo forte correlação com o comportamento. Conclusões: Os resultados apontam a necessidade de investir em medidas educativas, associadas a fiscalização, a melhoria das vias, pesquisas e aprimoramento da legislação. O monitoramento dos fatores de risco em escolares contribui substancialmente para apoiar intervenções das políticas públicas intersetoriais para a redução de morbimortalidade por trânsito.

ABSTRACT: Introduction: Land transport accidents (LTA) are the second cause of death in schoolchildren aged 13 to 17 years. The study aims to describe the risk factors for LTA in schoolchildren from the National School Health Survey (PeNSE) of 2015 and to evaluate the trend of selected indicators in the last three editions of PeNSE. Methodology: A descriptive study on risk factors for LTA in 2015, with PeNSE data and time series trends analysis, with age-adjusted regression tests of the 2009, 2012 and 2015 editions, in Brazilian capitals. Results: In 2015, 26.3% of ninth grade schoolchildren, mostly between 13 and 15 years of age, reported having been in a motor vehicle driven by someone who consumed alcohol and 32.4% had driven a motor vehicle; 30.7% of adolescents did not use seat belts in the back seat; and 16.8% of schoolchildren who ride motorcycles did not wear helmets. There was also a worsening of the indicators between 2009 and 2015, regarding driving a motor vehicle (1.0 percentage points) and having been driven by vehicle for consumption of alcoholic beverages (1.1 percentage points). Discussion: The LTA occurrence results from the interaction between roads, vehicles and users, and has a strong correlation with behavior. Conclusions: The results show the need to invest in educational measures, associated with supervision, the improvement of road infrastructure, research and improvement of legislation. The monitoring of risk factors in schoolchildren substantially contributes to support intersectoral public policies interventions to reduce morbidity and mortality in traffic.

Tendências de situações de violência vivenciadas por adolescentes brasileiros: Pesquisa Nacional de Saúde do Escolar 2009, 2012 e 2015 / Trends in violent situations experienced by Brazilian adolescents: National Adolescent Student Health Survey 2009, 2012, and 2015

RESUMO: Objetivo: Apresentar as tendências encontradas nas três últimas edições da Pesquisa Nacional de Saúde do Escolar (PeNSE) sobre situações de violência vivenciadas por escolares brasileiros. Metodologia: Estudo de séries temporais com recorte para as capitais brasileiras, utilizando as bases de dados da PeNSE de 2009, 2012 e 2015. Os indicadores avaliados foram: faltar às aulas por insegurança no trajeto casa-escola ou na escola; envolvimento em briga com arma de fogo ou arma branca; e agressão por adulto da família. Foram estimadas as prevalências dos indicadores para o total dos adolescentes, por sexo, tipo de escola e capitais. As tendências das prevalências foram estimadas por meio de regressão linear, ajustadas por idade. Resultados: Identificou-se tendência de aumento das prevalências, com significância estatística, para todos os indicadores de violência selecionados no período de 2009 a 2015, nas capitais brasileiras. Discussão: Os grupos mais vulneráveis foram escolares das escolas públicas; adolescentes do sexo masculino no caso do envolvimento em brigas com arma branca ou de fogo; e adolescentes do sexo feminino no caso de agressão física por familiar. Conclusão: A PeNSE contribuiu para identificar o aumento das prevalências de violências vividas pelos adolescentes, o que alerta para a necessidade de planejamento e implementação de políticas que contribuam para a prevenção de violência, promoção da saúde e da cultura de paz.

ABSTRACT: Objective: To present trends found in the last three editions of the National Adolescent Student Health Survey (Pesquisa Nacional de Saúde do Escolar - PeNSE) on violent situations experienced by Brazilian students. Methods: Time-series study with a focus on the Brazilian state capitals, using PeNSE databases of 2009, 2012, and 2015. The indicators evaluated were: missing classes due to insecurity in the home-school route or at school; involvement in a fight with firearm or melee weapon; and physical assault by an adult of the family. We estimated the prevalence of indicators according to the total number of adolescents, gender, school type, and capital. Trends in prevalence were estimated by linear regression, adjusted for age. Results: We identified a trend in increasing prevalence, with statistical significance, for all selected violence indicators in the period from 2009 to 2015, in Brazilian state capitals. Discussion: The most vulnerable groups were public schools students; male adolescents for involvement in fights with melee weapons or firearms; and female adolescents for physical assault by family members. Conclusion: PeNSE contributed to identifying the increase in the prevalence of violence experienced by adolescents, which alerts to the need of planning and implementing policies that help to prevent violence, and promote health and a culture of peace.

Estado nutricional, imagem corporal e associação com comportamentos extremos para controle de peso em adolescentes brasileiros, Pesquisa Nacional de Saúde do Escolar de 2015 / Nutritional status, body image, and their association with extreme weight control behaviors among Brazilian adolescents, National Adolescent Student Health Survey 2015

RESUMO: Introdução: Este estudo objetivou analisar a associação entre estado nutricional, percepção da imagem corporal e comportamentos extremos para controle de peso nos adolescentes. Metodologia: Estudo transversal analítico, realizado no Brasil a partir da Pesquisa Nacional de Saúde do Escolar (PeNSE) de 2015, com adolescentes de 13 a 17 anos. Estado nutricional e percepção da imagem corporal foram as variáveis independentes. As dependentes foram vômito ou uso de laxantes e uso de remédios e outras fórmulas para controle de peso nos últimos 30 dias. Modelos de regressão de Poisson foram empregados para associação, com uso de variáveis demográficas para controle. Resultados: 7,4% dos adolescentes (IC95% 6,7 - 8,2) relataram vômito ou uso de laxantes, sem diferença entre os sexos. A prevalência de uso de remédio e fórmulas foi maior entre meninos (7,8%; IC95% 6,6 - 8,9). A associação entre estado nutricional e comportamentos extremos não foi significativa; entretanto, a prevalência de vômito ou uso de laxantes foi 2,3 (IC95% 1,1 - 4,7) vezes maior em meninos e 5,3 (IC95% 3,3 - 8,6) vezes maior em meninas que se sentiam muito gordos(as), ao passo que uso de remédios e fórmulas foi 4,0 vezes (IC95% 2,3 - 7,1) maior em meninas que sentiam muito gordas. Conclusão: A percepção da imagem corporal parece ter maior influência na prática dos comportamentos extremos do que o estado nutricional. Estratégias envolvendo serviços de saúde e escolas têm grande potencialidade para ações que impactem positivamente na autoestima e na saúde dos estudantes.

ABSTRACT: Introduction: This study aimed to analyze the association between nutritional status, body image perception, and extreme weight control behaviors among adolescents. Methods: This is an analytical cross-sectional study conducted in Brazil based on the National Adolescent Student Health Survey (Pesquisa Nacional de Saúde do Escolar - PeNSE) of 2015, with adolescents aged 13 to 17 years. Nutritional status and body image perception were the independent variables. The two dependent variables were vomiting or laxative use and use of medicines and other formulas for weight control in the 30 days prior to data collection. We used Poisson regression models for association, with demographic variables for control. Results: 7.4% of adolescents (95%CI 6.7 - 8.2) reported vomiting or using laxatives, with no difference between genders. The prevalence of use of medicines and formulas was higher among boys (7.8%; 95%CI 6.6 - 8.9). The association between nutritional status and extreme behaviors was not significant. However, the prevalence of vomiting or laxative use for adolescents who considered themselves very fat was 2.3 (95%CI 1.1 - 4.7) times higher for boys and 5.3 (95%CI 3.3 - 8.6) times higher for girls, while the use of medicines and formulas was 4.0 (95%CI 2.3 - 7.1) times higher for girls who considered themselves very fat. Conclusion: Body image perception seems to have a greater influence on extreme behaviors than nutritional status. Strategies involving health services and schools have great potential to impact the self-esteem and health of students positively.

Cost of diseases related to alcohol consumption in the Brazilian Unified Health System.

OBJECTIVE: To estimate the direct costs associated to outpatient and hospital care of diseases related to alcohol consumption in the Brazilian Unified Health System. METHODS: Attributable populational risks were estimated for the selected diseases related to the use of 25 g/day or more of ethanol (risk consumption), considering a relative risk (RR) ≥ 1.20. The RR estimates were obtained from three meta-analysis. The risk consumption rates of the Brazilian population ≥ 18 years old were obtained by a national survey. Data from the Hospital Information System of SUS (HIS-SUS) were used to estimate the annual costs of the health system with the diseases included in the analysis. RESULTS: The total estimated costs for a year regarding diseases related to risk consumption were U$8,262,762 (US$4,413,670 and US$3,849,092, for outpatient and hospital care, respectively). CONCLUSIONS: Risk consumption of alcohol is an important economic and health problem, impacting significantly the health system and society.

ERICA: use of screens and consumption of meals and snacks by Brazilian adolescents.

OBJECTIVE To describe the length of exposure to screens and the prevalence of consumption of meals and snacks by Brazilian adolescents in front of screens. METHODS We evaluated 74,589 12 to 17-year old adolescents from 1,247 schools in 124 Brazilian municipalities. A self-administered questionnaire was used. Its segment regarding nutrition contained questions about using TV, computers, and video game systems, having meals while watching TV, and consuming snacks in front of screens. Consumption of meals and snacks in front of screens was analyzed according to the following variables: geographical region, gender, age range, type of school (public or private), and school shift. The prevalences and their respective 95% confidence intervals were estimated under a complex sampling design. RESULTS A great deal of the adolescents (51.8% IC95% 50.7-53.0) [corrected] reported spending two or more hours a day in front of screens. That habit was more frequent among male adolescents, private school students, morning shift students, and students from Brazil's South region. More than half of the adolescents (56.6%, 95%CI 55.4-57.8) reported almost always or always having meals in front of TV, and 39.6% (95%CI 38.8-40.5) of them said they consumed snacks in front of screens exactly as often. Both situations were the most prevalent ones among the girls, who attended public schools and were from Brazil's Midwest region. CONCLUSIONS Length of exposure to screens and consumption of meals and snacks almost always or always in front of screens are high among Brazilian adolescents. It is necessary to develop strategies aiming to reduce the length of screen use, considering the media reality that children and adolescents have been experiencing from earlier and earlier ages. That context must therefore be analyzed in an indissociable way.

ERICA: prevalence of healthy eating habits among Brazilian adolescents.

OBJECTIVE To describe the prevalence of eating habits considered healthy in adolescents according to sex, age, education level of the mother, school type, session of study, and geographic region. METHODS The assessed data come from the Study of Cardiovascular Risks in Adolescents (ERICA), a cross-sectional, national and school-based study. Adolescents of 1,247 schools of 124 Brazilian municipalities were evaluated using a self-administered questionnaire with a section on aspects related to eating behaviors. The following eating behaviors were considered healthy: consuming breakfast, drinking water, and having meals accompanied by parents or legal guardians. All prevalence estimates were presented proportionally, with their respective 95% confidence intervals. The Chi-square test was used to evaluate the differences in healthy eating habits prevalences according to other variables. The module survey of the Stata program version 13.0 was used to analyze complex data. RESULTS We evaluated 74,589 adolescents (72.9% of the eligible students). Of these, 55.2% were female, average age being 14.6 years (SD = 1.6). Among Brazilian adolescents, approximately half of them showed healthy eating habits when consuming breakfast, drinking five or more glasses of water a day, and having meals with parents or legal guardians. All analyzed healthy eating habits showed statistically significant differences by sex, age, type of school, session of study, or geographic region . CONCLUSIONS We suggest that specific actions of intersectoral approach are implemented for the dissemination of the benefits of healthy eating habits. Older female adolescents (15 to 17 years old) who studied in public schools, resided in the Southeast region, and whose mothers had lower education levels, should be the focus of these actions since they present lower frequencies concerning the evaluated healthy habits.

ERICA: use of screens and consumption of meals and snacks by Brazilian adolescents / ERICA: uso de telas e consumo de refeições e petiscos por adolescentes brasileiros

ABSTRACT OBJECTIVE To describe the length of exposure to screens and the prevalence of consumption of meals and snacks by Brazilian adolescents in front of screens. METHODS We evaluated 74,589 12 to 17-year old adolescents from 1,247 schools in 124 Brazilian municipalities. A self-administered questionnaire was used. Its segment regarding nutrition contained questions about using TV, computers, and video game systems, having meals while watching TV, and consuming snacks in front of screens. Consumption of meals and snacks in front of screens was analyzed according to the following variables: geographical region, gender, age range, type of school (public or private), and school shift. The prevalences and their respective 95% confidence intervals were estimated under a complex sampling design. RESULTS A great deal of the adolescents (73.5%, 95%CI 72.3-74.7) reported spending two or more hours a day in front of screens. That habit was more frequent among male adolescents, private school students, morning shift students, and students from Brazil’s South region. More than half of the adolescents (56.6%, 95%CI 55.4-57.8) reported almost always or always having meals in front of TV, and 39.6% (95%CI 38.8-40.5) of them said they consumed snacks in front of screens exactly as often. Both situations were the most prevalent ones among the girls, who attended public schools and were from Brazil’s Midwest region. CONCLUSIONS Length of exposure to screens and consumption of meals and snacks almost always or always in front of screens are high among Brazilian adolescents. It is necessary to develop strategies aiming to reduce the length of screen use, considering the media reality that children and adolescents have been experiencing from earlier and earlier ages. That context must therefore be analyzed in an indissociable way.

RESUMO OBJETIVO Descrever o tempo de exposição às telas e a prevalência de consumo de refeições e petiscos em frente a telas em adolescentes brasileiros. MÉTODOS Foram avaliados 74.589 adolescentes de 12 a 17 anos de 1.247 escolas em 124 municípios brasileiros. Foi utilizado questionário autopreenchível, cujo bloco sobre alimentação continha perguntas sobre o uso de TV, computador e videogames, realização de refeições assistindo TV e consumo de petiscos em frente a telas. O consumo de refeições e petiscos em frente a telas foi analisado segundo as variáveis: região geográfica, sexo, faixa etária, tipo de escola (pública ou particular) e turno de estudo. Foram estimadas prevalências e respectivos intervalos de confiança de 95%, considerando-se o desenho de amostra complexa. RESULTADOS Grande parte dos adolescentes (73,5%, IC95% 72,3-74,7) referiu passar duas ou mais horas por dia em frente às telas. Esse hábito foi mais frequente entre os adolescentes do sexo masculino, de escola particular, do turno da manhã e da região Sul do País. Mais da metade dos adolescentes (56,6%, IC95% 55,4-57,8) relatou realizar as refeições quase sempre ou sempre em frente à TV, e 39,6% (IC95% 38,8-40,5) consumiam petiscos em frente às telas com essa mesma frequência. Ambas as situações foram mais prevalentes entre as meninas, que estudavam na rede pública de ensino e da região Centro-Oeste. CONCLUSÕES O tempo de exposição às telas e o consumo de refeições e petiscos quase sempre ou sempre em frente a telas é elevado entre os adolescentes brasileiros. Faz-se necessário desenvolver estratégias que visem à redução do tempo de uso de telas, considerando a realidade midiática que crianças e adolescentes têm vivenciado de forma cada vez mais precoce, devendo-se, portanto, trabalhar esse contexto de forma indissociável.

ERICA: prevalence of healthy eating habits among Brazilian adolescents / ERICA: prevalência de comportamentos alimentares saudáveis em adolescentes brasileiros

ABSTRACT OBJECTIVE To describe the prevalence of eating habits considered healthy in adolescents according to sex, age, education level of the mother, school type, session of study, and geographic region. METHODS The assessed data come from the Study of Cardiovascular Risks in Adolescents (ERICA), a cross-sectional, national and school-based study. Adolescents of 1,247 schools of 124 Brazilian municipalities were evaluated using a self-administered questionnaire with a section on aspects related to eating behaviors. The following eating behaviors were considered healthy: consuming breakfast, drinking water, and having meals accompanied by parents or legal guardians. All prevalence estimates were presented proportionally, with their respective 95% confidence intervals. The Chi-square test was used to evaluate the differences in healthy eating habits prevalences according to other variables. The module survey of the Stata program version 13.0 was used to analyze complex data. RESULTS We evaluated 74,589 adolescents (72.9% of the eligible students). Of these, 55.2% were female, average age being 14.6 years (SD = 1.6). Among Brazilian adolescents, approximately half of them showed healthy eating habits when consuming breakfast, drinking five or more glasses of water a day, and having meals with parents or legal guardians. All analyzed healthy eating habits showed statistically significant differences by sex, age, type of school, session of study, or geographic region . CONCLUSIONS We suggest that specific actions of intersectoral approach are implemented for the dissemination of the benefits of healthy eating habits. Older female adolescents (15 to 17 years old) who studied in public schools, resided in the Southeast region, and whose mothers had lower education levels, should be the focus of these actions since they present lower frequencies concerning the evaluated healthy habits.

RESUMO OBJETIVO Descrever a prevalência de comportamentos alimentares considerados saudáveis em adolescentes brasileiros, segundo sexo, idade, escolaridade da mãe, tipo de escola, turno de estudo e região geográfica. MÉTODOS Os dados analisados provêm do Estudo de Riscos Cardiovasculares em Adolescentes (ERICA), estudo transversal, nacional e de base escolar. Foram avaliados adolescentes de 1.247 escolas em 124 municípios brasileiros, utilizando questionário autopreenchível que incluía um bloco sobre aspectos relacionados ao comportamento alimentar. Foram considerados saudáveis os seguintes comportamentos alimentares: consumo de café da manhã, ingestão de água e realização de refeições com os pais ou responsáveis. As estimativas das prevalências foram apresentadas em proporções, com seus respectivos intervalos de confiança de 95%. O teste Qui-quadrado foi utilizado para avaliar a diferença das prevalências dos comportamentos alimentares saudáveis de acordo com as demais variáveis. Utilizou-se o módulosurvey do programa Stata versão 13,0 para análise de dados de amostra complexa. RESULTADOS Foram avaliados 74.589 adolescentes (72,9% dos alunos elegíveis). Desses, 55,2% eram do sexo feminino e a média de idade foi de 14,6 anos (DP = 1,6). Entre os adolescentes brasileiros, aproximadamente metade apresentou comportamentos alimentares saudáveis quanto ao consumo de café da manhã, realização de refeições com os pais ou responsáveis e ingestão de cinco ou mais copos de água por dia. Todos os comportamentos alimentares saudáveis analisados apresentaram diferença estatisticamente significativa por sexo, idade, tipo de escola, turno de estudo ou região geográfica. CONCLUSÕES Sugere-se que ações específicas, de abordagem intersetorial, sejam implementadas para a disseminação dos benefícios dos comportamentos alimentares saudáveis. Adolescentes do sexo feminino, mais velhos (15 a 17 anos), cujas mães têm escolaridade mais baixa, alunos de escolas públicas e da região Sudeste, deveriam ser o foco dessas ações já que são os que apresentam menores frequências dos comportamentos saudáveis analisados.

Cost of diseases related to alcohol consumption in the Brazilian unified health system / Custos de doenças relacionadas ao consumo de álcool no sistema único de saúde

ABSTRACT OBJECTIVE To estimate the direct costs associated to outpatient and hospital care of diseases related to alcohol consumption in the Brazilian Unified Health System. METHODS Attributable populational risks were estimated for the selected diseases related to the use of 25 g/day or more of ethanol (risk consumption), considering a relative risk (RR) ≥ 1.20. The RR estimates were obtained from three meta-analysis. The risk consumption rates of the Brazilian population ≥ 18 years old were obtained by a national survey. Data from the Hospital Information System of SUS (HIS-SUS) were used to estimate the annual costs of the health system with the diseases included in the analysis. RESULTS The total estimated costs for a year regarding diseases related to risk consumption were U$8,262,762 (US$4,413,670 and US$3,849,092, for outpatient and hospital care, respectively). CONCLUSIONS Risk consumption of alcohol is an important economic and health problem, impacting significantly the health system and society.

RESUMO OBJETIVO Estimar os custos diretos associados ao atendimento ambulatorial e hospitalar de doenças relacionadas com o consumo de álcool no Sistema Único de Saúde brasileiro. MÉTODOS Riscos atribuíveis populacionais foram calculados para doenças selecionadas relacionadas ao uso de 25 g/dia ou mais de etanol (consumo de risco), considerando-se o risco relativo (RR) ≥ 1,.20. As estimativas de RR foram obtidas a partir de três meta-análises e as taxas de consumo de risco em brasileiros ≥ 18 anos obtidos em pesquisa nacional. Os dados do Sistema de Informações Hospitalares do SUS (SIH-SUS) e do Sistema de Informações Ambulatoriais do SUS (SIA-SUS) foram utilizados para estimar os custos anuais do SUS com as doenças incluídas na análise. RESULTADOS Os custos totais estimados em um ano com todas as doenças relacionadas com consumo de risco foram US$8.262.762 (US$4.413.670 e US$3.849.092 para pacientes ambulatoriais e internados, respectivamente). CONCLUSÕES Consumo de risco de álcool representa importante problema econômico e de saúde, com um impacto significativo para o sistema de saúde e para a sociedade.

The costs of overweight and obesity-related diseases in the Brazilian public health system: cross-sectional study.

BACKGROUND: Obesity is a major global epidemic and a burden to society and health systems. It is well known risk factor for a number of chronic medical conditions with high morbidity and mortality. This study aimed to provide an estimate of the direct costs associated to outpatient and inpatient care of overweight and obesity related diseases in the perspective of the Brazilian Health System (SUS). METHODS: Population attributable risk (PAR) was calculated for selected diseases related to overweight and obesity and with the following parameters: Relative risk (RR) ≥ 1.20 or RR ≥ 1.10 and < 1.20, but important problem of public health due its high prevalence. After a broad search in the literature, two meta-analysis were selected to provide RR for PAR calculation. The prevalence rates of overweight and obesity in Brazilians with ≥ 18 years were obtained from large national survey. The national health database (DATASUS) was used to estimate the annual cost of the Brazilian Unified Health System (SUS) with the diseases included in the analysis. The extracted values were stratified by sex, type of service (inpatient or outpatient care) and year. Data were collected from 2008 to 2010 and the results reflect the average of 3 years. Brazilian costs were converted into US dollars during the analysis using a purchasing power parity basis (2010). RESULTS: The estimated total costs in one year with all diseases related to overweight and obesity are US$ 2,1 billion; US$ 1,4 billion (68.4% of total costs) due to hospitalizations and US$ 679 million due to ambulatory procedures. Approximately 10% of these cost is attributable to overweight and obesity. CONCLUSION: The results confirm that overweight and obesity carry a great economic burden for Brazilian health system and for the society. The knowledge of these costs will be useful for future economic analysis of preventive and treatment interventions.

Bioelectrical impedance values among indigenous children and adolescents in Rio Grande do Sul, Brazil.

OBJECTIVE: To describe the nutritional status of indigenous children and adolescents in Rio Grande do Sul, Brazil, through bioelectrical values, and to compare the nutritional classifications of the anthropometric method to those of the body composition method. METHODS: A cross-sectional survey was conducted of 3 204 subjects at 35 schools in the 12 Kaingang indigenous lands of Rio Grande do Sul, Brazil. Following World Health Organization recommendations, the weight and height (H) of each subject was measured twice and the body mass index/age (BMI/A) was classified. Body composition was assessed by Bioelectrical Impedance Vector Analysis (BIVA). Resistance (R) and reactance (Xc) were estimated using a bioelectrical impedance analyzer. Divergences between these two methods were performed on RXc graph. RESULTS: Of the sample, 56.8% were adolescents and 50.6% were males. The mean values of phase angle were higher in adolescents, in males, and in individuals overweight by BMI/A. Mean values of R, Xc, R/H, and Xc/H were higher among children and among those with BMI/A < +2 z scores. Divergences in overweight classification were: male children, 94.6%; male adolescents, 77.1%; female children, 85.4%; and female adolescents, 94.8%. CONCLUSIONS: The mean values of bioelectrical measures observed among the Kaingang children and adolescent were similar to those found for different populations in other studies. For both gender and age groups, differences were observed between nutritional classifications by BMI/age and by BIVA. These results reinforce the importance of employing multiple techniques, such as anthropometry and BIVA, when conducting nutritional assessments of a population.

Bioelectrical impedance values among indigenous children and adolescents in Rio Grande do Sul, Brazil / Valores de impedancia bioeléctrica en niños y adolescentes indígenas en Rio Grande do Sul, Brasil

OBJECTIVE: To describe the nutritional status of indigenous children and adolescents in Rio Grande do Sul, Brazil, through bioelectrical values, and to compare the nutritional classifications of the anthropometric method to those of the body composition method. METHODS: A cross-sectional survey was conducted of 3 204 subjects at 35 schools in the 12 Kaingang indigenous lands of Rio Grande do Sul, Brazil. Following World Health Organization recommendations, the weight and height (H) of each subject was measured twice and the body mass index/age (BMI/A) was classified. Body composition was assessed by Bioelectrical Impedance Vector Analysis (BIVA). Resistance (R) and reactance (Xc) were estimated using a bioelectrical impedance analyzer. Divergences between these two methods were performed on RXc graph. RESULTS: Of the sample, 56.8 percent were adolescents and 50.6 percent were males. The mean values of phase angle were higher in adolescents, in males, and in individuals overweight by BMI/A. Mean values of R, Xc, R/H, and Xc/H were higher among children and among those with BMI/A < +2 z scores. Divergences in overweight classification were: male children, 94.6 percent; male adolescents, 77.1 percent; female children, 85.4 percent; and female adolescents, 94.8 percent. CONCLUSIONS: The mean values of bioelectrical measures observed among the Kaingang children and adolescent were similar to those found for different populations in other studies. For both gender and age groups, differences were observed between nutritional classifications by BMI/age and by BIVA. These results reinforce the importance of employing multiple techniques, such as anthropometry and BIVA, when conducting nutritional assessments of a population.

OBJETIVO: Describir el estado nutricional de niños y adolescentes indígenas en Rio Grande do Sul, Brasil, mediante los valores de impedancia bioeléctrica y comparar las clasificaciones nutricionales del método antropométrico con las del método de composición corporal. MÉTODOS: Se llevó a cabo un estudio transversal en 3 204 participantes de 35 escuelas de los 12 territorios indígenas habitados por el pueblo kaingang (o guayaná) del estado de Rio Grande do Sul (Brasil). Según las recomendaciones de la Organización Mundial de la Salud, se midió el peso y la talla (T) de cada participante en dos oportunidades y se clasificó el índice de masa corporal (IMC) según la edad. La composición corporal se evaluó mediante análisis vectorial de impedancia bioeléctrica. La resistencia (R) y la reactancia (Xc) se calcularon con un analizador de impedancia bioeléctrica. Las divergencias entre estos dos métodos se analizaron con un gráfico RXc. RESULTADOS: De la muestra, 56,8 por ciento eran adolescentes y 50,6 por ciento eran varones. Los valores medios del ángulo de fase fueron mayores en los adolescentes, en los varones y en los individuos con sobrepeso según el IMC/edad. Los valores medios de R, Xc, R/T y Xc/T fueron mayores en los niños y en las personas con puntajes z de IMC/edad < +2. Se observaron las siguientes divergencias en la clasificación del sobrepeso: 94,6 por ciento para los niños, 77,1 por ciento para los adolescentes, 85,4 por ciento para las niñas y 94,8 por ciento para las adolescentes. CONCLUSIONES: Los valores medios de las medidas de impedancia bioeléctrica observados en niños y adolescentes kaingang fueron similares a los encontrados en diferentes poblaciones en otros estudios. Se observaron diferencias entre las clasificaciones nutricionales por IMC/edad y por análisis vectorial de impedancia bioeléctrica en ambos sexos y grupos etarios. Estos resultados destacan la importancia de emplear múltiples técnicas, como la antropometría y el análisis vectorial de impedancia bioeléctrica, cuando se efectúan evaluaciones nutricionales de una determinada población.