Evaluation of tourism competitiveness and mechanisms of spatial differentiation in Xinjiang, China.

Evaluation of tourism competitiveness is useful for measuring the level of regional tourism development. It is of great importance to understand the advantages and disadvantages of tourism development correctly and formulate corresponding development strategies. To investigate tourism competitiveness, this paper established an evaluation index system, including tourism development competitiveness, tourism resource competitiveness, and tourism-support competitiveness, for 14 prefectures and cities in Xinjiang in China. The characteristics and laws of spatial differentiation were analyzed. Factor analysis was applied to examine the spatial differentiation of regional tourism competitiveness. The results showed an obvious spatial differentiation in tourism competitiveness among the 14 prefectures and cities. In terms of development competitiveness, Yili and Urumqi constituted the spatial center, followed by Changji, Altay, and Ba Prefecture. As the provincial capital, Urumqi has political, economic, cultural, transportation, and geographic advantages, but its competitiveness is not prominent in terms of monopoly and efficiency. In terms of resource competitiveness, Yili is the core attraction, while Urumqi, Kashgar, Altay, and Ba Prefecture are dominant attractions. With respect to supporting competitiveness, Bo Prefecture has high value, followed by Urumqi City and Aksu. Hetian and Ke Prefecture have the lowest values. The comprehensive competitiveness of tourism is centered on Yili. Urumqi and Bo Prefecture are subcenters, and Changji, Altay, Ba Prefecture, Aksu, and Kashgar are characterized as multi-polar competition areas. Using the KMO and Bartlett's sphericity tests, the cumulative contribution variance of the eigenvalues of the eight factors extracted by the maximum variance rotation method was found to be 92.714%. Socio-economic conditions, tourism resources, infrastructure construction, regional cultural influence, ecological environment carrying capacity, tertiary industry development, tourism service level, and living security system are the main driving factors affecting the spatial differentiation of tourism competitiveness in Xinjiang. Analyzing the spatial evolution characteristics and the driving factors of the regional tourism competitiveness in Xinjiang, this paper seeks to promote the optimal allocation of tourism production factors in the macro regional system, and provide theoretical guidance and an empirical basis for the comprehensive and harmonic development of regional tourism.

Quantitative assessment of inter-individual variability in fMRI-based human brain atlas.

BACKGROUND: Inter-individual variability is an inherent and ineradicable feature of group-level brain atlases that undermines their reliability for clinical and other applications. To date, there have been no reports quantifying inter-individual variability in brain atlases. METHODS: In the present study, we compared inter-individual variability in nine brain atlases by task-based functional magnetic resonance imaging (MRI) mapping of motor and temporal lobe language regions in both cerebral hemispheres. We analyzed complete motor and language task-based fMRI and T1 data for 893 young, healthy subjects in the Human Connectome Project database. Euclidean distances (EDs) between hotspots in specific brain regions were calculated from task-based fMRI and brain atlas data. General linear model parameters were used to investigate the influence of different brain atlases on signal extraction. Finally, the inter-individual variability of ED and extracted signals and interdependence of relevant indicators were statistically evaluated. RESULTS: We found that inter-individual variability of ED varied across the nine brain atlases (P<0.0001 for motor regions and P<0.0001 for language regions). There was no correlation between parcel number and inter-individual variability in left to right (LtoR; P=0.7959 for motor regions and P=0.2002 for language regions) and right to left (RtoL; P=0.7654 for motor regions and P=0.3544 for language regions) ED; however, LtoR (P≤0.0001) and RtoL (P≤0.0001) inter-individual variability differed according to brain region: the LtoR (P=0.0008) and RtoL (P=0.0004) inter-individual variability was greater for the right hand than for the left hand, the LtoR (P=0.0019) and RtoL (P=0.0179) inter-individual variability was greater for the right language than for the left language, but there was no such difference between the right foot and left foot (LtoR, P=0.2469 and RtoL, P=0.6140). Inter-individual variability in one motor region was positively correlated with mean values in the other three motor regions (left hand, P=0.0145; left foot, P=0.0103; right hand, P=0.1318; right foot, P=0.3785). Inter-individual variability in language region was positively correlated with mean values in the four motor regions (left language, P=0.0422; right language, P=0.0514). Signal extraction for LtoR (P<0.0001) and RtoL (P<0.0001) varied across the nine brain atlases, which also showed differences in inter-individual variability. CONCLUSIONS: These results underscore the importance of quantitatively assessing the inter-individual variability of a brain atlas prior to use, and demonstrate that mapping motor regions by task-based fMRI is an effective method for quantitatively assessing the inter-individual variability in a brain atlas.

The Application of Wavelet-Domain Hidden Markov Tree Model in Diabetic Retinal Image Denoising.

The wavelet-domain Hidden Markov Tree Model can properly describe the dependence and correlation of fundus angiographic images' wavelet coefficients among scales. Based on the construction of the fundus angiographic images Hidden Markov Tree Models and Gaussian Mixture Models, this paper applied expectation-maximum algorithm to estimate the wavelet coefficients of original fundus angiographic images and the Bayesian estimation to achieve the goal of fundus angiographic images denoising. As is shown in the experimental result, compared with the other algorithms as mean filter and median filter, this method effectively improved the peak signal to noise ratio of fundus angiographic images after denoising and preserved the details of vascular edge in fundus angiographic images.