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1.
Zhongguo Zhong Yao Za Zhi ; 48(5): 1203-1211, 2023 Mar.
Artigo em Chinês | MEDLINE | ID: mdl-37005804

RESUMO

To study the residue and dietary risk of propiconazole in Panax notoginseng and the effects on physiological and bioche-mical properties of P. notoginseng, we conducted foliar spraying of propiconazole on P. notoginseng in pot experiments. The physiolo-gical and biochemical properties studied included leaf damage, osmoregulatory substance content, antioxidant enzyme system, non-enzymatic system, and saponin content in the main root. The results showed that at the same application concentration, the residual amount of propiconazole in each part of P. notoginseng increased with the increase in the times of application and decreased with the extension of harvest interval. After one-time application of propiconazole according to the recommended dose(132 g·hm~(-2)) for P. ginseng, the half-life was 11.37-13.67 days. After 1-2 times of application in P. notoginseng, propiconazole had a low risk of dietary intake and safety threat to the population. The propiconazole treatment at the recommended concentration and above significantly increased the malondialdehyde(MDA) content, relative conductivity, and osmoregulatory substances and caused the accumulation of reactive oxygen species in P. notoginseng leaves. The propiconazole treatment at half(66 g·hm~(-2)) of the recommended dose for P. ginseng significantly increased the activities of superoxide dismutase(SOD), peroxidase(POD), and catalase(CAT) in P. notoginseng leaves. The propiconazole treatment at 132 g·hm~(-2) above inhibited the activities of glutathione reductase(GR) and glutathione S-transferase(GST), thereby reducing glutathione(GSH) content. Proconazole treatment changed the proportion of 5 main saponins in the main root of P. notoginseng. The treatment with 66 g·hm~(-2) propiconazole promoted the accumulation of saponins, while that with 132 g·hm~(-2) and above propiconazole significantly inhibited the accumulation of saponins. In summary, using propiconazole at 132 g·hm~(-2) to prevent and treat P. notoginseng diseases will cause stress on P. notoginseng, while propiconazole treatment at 66 g·hm~(-2) will not cause stress on P. notoginseng but promote the accumulation of saponins. The effect of propiconazole on P. notoginseng diseases remains to be studied.


Assuntos
Panax notoginseng , Panax , Saponinas , Panax notoginseng/química , Antioxidantes/farmacologia , Saponinas/farmacologia , Glutationa , Medição de Risco
2.
Ecotoxicol Environ Saf ; 233: 113348, 2022 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-35240504

RESUMO

UPLC-MS/MS and GC-MS/MS were used to establish a method to simultaneously determine various pesticide residues in Panax notoginseng. Results showed that the limits of detection of 249 pesticides were all 5-10 µg/kg. The detection rate of pesticides in 121 P. notoginseng samples was 93.39%, and 19 pesticides were detected. According to the US Code of Federal Regulations, the Chinese Pharmacopoeia recommended algorithm, and the Japanese "positive list system", the pass rates of pesticide residues were 100%, 99.17%, and 89.26%, respectively. The chronic risk quotient (ADI%) and acute risk quotient (ARfD%) of P. notoginseng were 0.00-0.12% and 0.00-0.15%, respectively. In summary, the detection method established in this study can be used for routine analysis of various P. notoginseng pesticide residues. The pesticide residues in the main root samples of P. notoginseng were at a safe level and unlikely pose health risks to consumers.


Assuntos
Panax notoginseng , Resíduos de Praguicidas , Cromatografia Líquida , Ingestão de Alimentos , Contaminação de Alimentos/análise , Panax notoginseng/química , Resíduos de Praguicidas/análise , Medição de Risco , Espectrometria de Massas em Tandem/métodos
3.
Zhongguo Zhong Yao Za Zhi ; 41(5): 776-785, 2016 Mar.
Artigo em Chinês | MEDLINE | ID: mdl-28875627

RESUMO

Through the markets investigations and literature surveying, this paper investigates and analyzes the qualitative characteristics and commodity condition of Panax notoginseng. And the samples collected from market and origin were analyzed in order to revise the commodity specification and grade standard of P. notoginseng combined with production practice. In this paper, the authors divide the P. notoginseng into 4 commodity specification which are root (including Cunqi and Dongqi ), Rhizome and rootlet according to different parts and harvest time. And the root were divided into 8 grade which are 20, 30, 40, 60, 80, 120, countless and substandard. The density and internal components between the different commodity specification and grade of P. notoginseng were also compared. As well as the effect of different producing area, cultivation years and harvesting time on the commodity specification and grade of P. notoginseng were researched. On this basis, we revise and improve the commodity specification and grade standard of P. notoginseng. Moreover, we suggest the quality control indexes of P. notoginseng should be developed according to the different medicinal part and commodity specification in CHP. In order to guide the standardized production of traditional Chinese medicine and ensure the quality of medicinal materials, the cultivation years and density of each medicinal materials should also be indicated in CHP.


Assuntos
Medicamentos de Ervas Chinesas/química , Panax notoginseng/química , Panax notoginseng/classificação , Medicamentos de Ervas Chinesas/economia , Medicina Tradicional Chinesa/economia , Medicina Tradicional Chinesa/normas , Raízes de Plantas/química , Raízes de Plantas/classificação , Controle de Qualidade
4.
Zhongguo Zhong Yao Za Zhi ; 39(4): 553-7, 2014 Feb.
Artigo em Chinês | MEDLINE | ID: mdl-25204122

RESUMO

Sanqi (Panax notoginseng) is a valuable unique herb, and is also one of the very fast developed varieties of traditional Chinese medicines in recent years with increasing role in traditional Chinese medicine industry. This paper summarized the main experience, industry development and present situation, pointed out the main problems existing in the industry development. On this basis, we put forward the targets and measures for the development of the Sanqi industry in to provide decision-making reference for the sustainable development of the Sanqi industry in China.


Assuntos
Indústria Farmacêutica/tendências , Medicina Tradicional Chinesa/tendências , Panax notoginseng/crescimento & desenvolvimento , China , Indústria Farmacêutica/economia , Medicamentos de Ervas Chinesas/análise , Medicamentos de Ervas Chinesas/economia , Medicina Tradicional Chinesa/economia , Panax notoginseng/química
5.
Zhongguo Zhong Yao Za Zhi ; 38(20): 3453-7, 2013 Oct.
Artigo em Chinês | MEDLINE | ID: mdl-24490552

RESUMO

The purpose of the article is to apply a binary logistic model to analyze the major factors, which influence Chinese medicinal herb growers' willingness to use green pesticides by using survey data collected in Wenshan, Yunnan Province. The results indicate that, output per capita, average pesticide cost per mu, cognition of pesticide residues, expectations on Panax notoginseng prices, cognition of pesticides' effect of pests control, cognition of P. notoginseng prices of low pesticide residues have a significant influence on growers' willingness to use green pesticides. According to the analysis above, some proposals for enhancing Chinese medicinal herb growers' willingness to use green pesticides are put forward, such as, moving toward the intensive planting systems, fetching down the pieces of green pesticides, emphasizing and propagating the advantages of green pesticides, keeping the prices of Chinese medicinal herb running at steady rates.


Assuntos
Atitude , Agricultura Orgânica , Panax notoginseng/crescimento & desenvolvimento , Adulto , China , Feminino , Humanos , Masculino , Agricultura Orgânica/economia , Praguicidas/análise , Praguicidas/economia , Doenças das Plantas/prevenção & controle , Plantas Medicinais/crescimento & desenvolvimento , Recursos Humanos , Adulto Jovem
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