RESUMO
INTRODUCTION: The Mtwo rotary system was designed to be used at full length without performing previous cervical enlargement or creating a manual glide path. However, to our knowledge, no study has investigated whether preflaring influences instrument fatigue. The purpose of this clinical study was thus to evaluate the incidence of separation of Mtwo instruments during the preparation of mandibular and maxillary molars and bicuspids that was preceded by cervical preflaring. METHODS: A total of 556 treatments were performed by 6 endodontists after calibration. Cervical enlargement and exploration with hand files were undertaken before using the rotary files. The canals were negotiated with small K-type hand files. Cervical and middle thirds were prepared with hand files and Gates-Glidden burs. Irrigation was performed with 2 mL of 2.5% NaOCl after each instrument. The working length was established, and the apical third was prepared with Flexofiles until a #15 file could reach the working length, establishing a glide path. The Mtwo instruments were used following manufacturer's recommendations and disposed of after being used in 5 teeth. Each file was examined under ×8 magnification after use. In cases of file deformation or separation, the entire file kit was no longer used, except when using the 10.04 file. Because of its high failure rate, which is well-established in the related literature, this instrument could be replaced at any time. RESULTS: Separation and deformation rates were 1.98% and 28.78%, respectively. Ten of the total separations observed occurred with the 10.04 file (90.01%) and one with the 15.05 file (9.09%). CONCLUSIONS: The use of Mtwo rotary instruments preceded by cervical preflaring with manual files and Gates-Glidden burs provides a low separation incidence.
Assuntos
Cavidade Pulpar/patologia , Preparo de Canal Radicular/instrumentação , Dente Pré-Molar/patologia , Ligas Dentárias/química , Ácido Edético/uso terapêutico , Desenho de Equipamento , Falha de Equipamento , Humanos , Dente Molar/patologia , Estudos Prospectivos , Irrigantes do Canal Radicular/uso terapêutico , Hipoclorito de Sódio/uso terapêutico , Aço Inoxidável/química , Estresse Mecânico , Propriedades de Superfície , Ápice Dentário/patologiaRESUMO
INTRODUCTION: The change in the heparin solution trade mark in Brazil that had been commonly used in cardiac surgery has shown increased number in the coagulopathy, re-exploration and other side effects in our Institution and others. METHODS: All four different heparin solutions available in the Brazilian market were studied in the Connective Tissue Lab, HUCFF, UFRJ and compared to the Liquemine (out of the market) and the international control solution. All samples were evaluated by magnetic nuclear resonance as well as their anticoagulant effectiveness. RESULTS: There were significant differences among them regarding the anticoagulant activity. It was also observed contamination with other dermatan sulfate, samples chemically degraded and with significant change in the molecular weight. CONCLUSION: Among the studied samples, none of them can offer security in cardiac surgeries on pump. None of them has demonstrated similar quality to Liquemine, which is not available in the Brazilian market.
Assuntos
Anticoagulantes/normas , Procedimentos Cirúrgicos Cardiovasculares , Indústria Farmacêutica/normas , Heparina/normas , Anticoagulantes/sangue , Anticoagulantes/química , Brasil , Cromatografia em Gel , Dermatan Sulfato/sangue , Contaminação de Medicamentos , Heparina/sangue , Heparina/química , Ácidos Hexurônicos/sangue , Humanos , Espectroscopia de Ressonância Magnética , Peso Molecular , Tempo de Tromboplastina Parcial , Controle de Qualidade , Padrões de ReferênciaRESUMO
INTRODUÇÃO: A mudança na marca da heparina rotineiramente utilizada nas cirurgias cardíacas no Brasil tem sido acompanhada por aumento do número de casos de discrasia sanguínea, aumento de reoperações e efeitos adversos em nossa Instituição e em outras. MÉTODOS: Foram avaliadas no Laboratório de Tecido Conjuntivo do HUCFF/UFRJ, quatro preparações disponíveis e comparadas à heparina retirada do mercado (Liquemine) e ao padrão de controle internacional. As preparações de heparina foram submetidas à ressonância nuclear magnética para avaliação da integridade estrutural, bem como avaliação de sua eficácia anticoagulante. RESULTADOS: Houve diferença significativa quanto à atividade anticoagulante entre as amostras. Também se observou a presença de contaminação com dermatam sulfato, amostras degradadas quimicamente e com significativa alteração do peso molecular. CONCLUSÃO: Das amostras estudadas, nenhuma atendeu aos requisitos de segurança para utilização em cirurgias cardíacas com circulação extracorpórea. Nenhuma delas apresentou a qualidade semelhante ao Liquemine, não mais disponível no mercado brasileiro.
INTRODUCTION: The change in the heparin solution trade mark in Brazil that had been commonly used in cardiac surgery has shown increased number in the coagulopathy, re-exploration and other side effects in our Institution and others. METHODS: All four different heparin solutions available in the Brazilian market were studied in the Connective Tissue Lab, HUCFF, UFRJ and compared to the Liquemine (out of the market) and the international control solution. All samples were evaluated by magnetic nuclear resonance as well as their anticoagulant effectiveness. RESULTS: There were significant differences among them regarding the anticoagulant activity. It was also observed contamination with other dermatan sulfate, samples chemically degraded and with significant change in the molecular weight. CONCLUSION: Among the studied samples, none of them can offer security in cardiac surgeries on pump. None of them has demonstrated similar quality to Liquemine, which is not available in the Brazilian market.