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Consult Pharm ; 26(1): 43-7, 2011 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21224198

RESUMO

OBJECTIVE: To identify whether veterans receiving androgen-deprivation therapy (ADT) are screened at any time by bone mass measurement. DESIGN: Cross-sectional study. SETTING: Veterans Administration Tennessee Valley Healthcare System (VA-TVHS). PATIENTS: All male veterans who received at least one dose of goserelin or leuprolide within the fiscal years October 1, 2005, through September 30, 2009. INTERVENTIONS: Data from patients' charts were extracted for demographic information (race, age, and weight prior to the initial injection); date of initiation of therapy; the use of calcium, vitamin D, bisphosphonate, or calcitonin therapy; and documented bone-mineral density testing. MAIN OUTCOME MEASURE: To determine whether veterans receiving ADT with goserelin or leuprolide for prostate cancer were screened at any time for BMD more or less than rates as documented in previous literature. RESULTS: 22.8% of veterans were screened for BMD, which was statistically significant when compared with results found in previous literature. CONCLUSION: Although rates of BMD testing were higher at VA-TVHS compared with previous literature, this rate is still low given the well-known risk of accelerated osteoporosis associated with ADT.


Assuntos
Androgênios/deficiência , Antineoplásicos Hormonais/efeitos adversos , Antineoplásicos Hormonais/uso terapêutico , Gosserrelina/efeitos adversos , Leuprolida/efeitos adversos , Osteoporose/induzido quimicamente , Idoso , Antagonistas de Androgênios/efeitos adversos , Antagonistas de Androgênios/uso terapêutico , Densidade Óssea/efeitos dos fármacos , Estudos Transversais , Gosserrelina/uso terapêutico , Humanos , Leuprolida/uso terapêutico , Masculino , Osteoporose/metabolismo , Neoplasias da Próstata/tratamento farmacológico , Medição de Risco , Veteranos
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