Clinical research staff perceptions on a natural language processing-driven tool for eligibility prescreening: An iterative usability assessment.

BACKGROUND: Participant recruitment is a barrier to successful clinical research. One strategy to improve recruitment is to conduct eligibility prescreening, a resource-intensive process where clinical research staff manually reviews electronic health records data to identify potentially eligible patients. Criteria2Query (C2Q) was developed to address this problem by capitalizing on natural language processing to generate queries to identify eligible participants from clinical databases semi-autonomously. OBJECTIVE: We examined the clinical research staff's perceived usability of C2Q for clinical research eligibility prescreening. METHODS: Twenty clinical research staff evaluated the usability of C2Q using a cognitive walkthrough with a think-aloud protocol and a Post-Study System Usability Questionnaire. On-screen activity and audio were recorded and transcribed. After every-five evaluators completed an evaluation, usability problems were rated by informatics experts and prioritized for system refinement. There were four iterations of system refinement based on the evaluation feedback. Guided by the Organizational Framework for Intuitive Human-computer Interaction, we performed a directed deductive content analysis of the verbatim transcriptions. RESULTS: Evaluators aged from 24 to 46 years old (33.8; SD: 7.32) demonstrated high computer literacy (6.36; SD:0.17); female (75 %), White (35 %), and clinical research coordinators (45 %). C2Q demonstrated high usability during the final cycle (2.26 out of 7 [lower scores are better], SD: 0.74). The number of unique usability issues decreased after each refinement. Fourteen subthemes emerged from three themes: seeking user goals, performing well-learned tasks, and determining what to do next. CONCLUSIONS: The cognitive walkthrough with a think-aloud protocol informed iterative system refinement and demonstrated the usability of C2Q by clinical research staff. Key recommendations for system development and implementation include improving system intuitiveness and overall user experience through comprehensive consideration of user needs and requirements for task completion.

Moving beyond Table 1: A critical review of the literature addressing social determinants of health in chronic condition symptom cluster research.

Variability in the symptom experience in patients diagnosed with chronic conditions may be related to social determinants of health (SDoH). The purpose of this critical review was to (1) summarize the existing literature on SDoH and symptom clusters (i.e., multiple, co-occurring symptoms) in patients diagnosed with common chronic conditions, (2) evaluate current variables and measures used to represent SDoH, (3) identify gaps in the evidence base, and (4) provide recommendations for the incorporation of SDoH into future symptom cluster research. We identified 118 articles including information on SDoH in chronic condition symptom cluster research. Articles primarily focused on cancer populations. Few articles had the explicit purpose of investigating relationships between SDoH and symptom clusters, and the inclusion of SDoH was often limited to variables used to describe samples. Future studies should be designed to "move beyond Table 1" in their utilization of SDoH as variables and examine relationships between SDoH and symptom clusters. Attention should be paid to the appropriateness of measures being used to collect information on SDoH, and analysis methods that estimate causal connections between variables should be considered. Research regarding the relationship of SDoH with symptom clusters in patients with chronic conditions has the potential to reveal mechanisms of symptom disparities and guide changes to alleviate these disparities.

Informatics and data science perspective on Future of Nursing 2020-2030: Charting a pathway to health equity.

The Future of Nursing 2020 to 2030 report explicitly addresses the need for integration of nursing expertise in designing, generating, analyzing, and applying data to support initiatives focused on social determinants of health (SDOH) and health equity. The metrics necessary to enable and evaluate progress on all recommendations require harnessing existing data sources and developing new ones, as well as transforming and integrating data into information systems to facilitate communication, information sharing, and decision making among the key stakeholders. We examine the recommendations of the 2021 report through an interdisciplinary lens that integrates nursing, biomedical informatics, and data science by addressing three critical questions: (a) what data are needed?, (b) what infrastructure and processes are needed to transform data into information?, and (c) what information systems are needed to "level up" nurse-led interventions from the micro-level to the meso- and macro-levels to address social determinants of health and advance health equity?

Elder Abuse in American Indian Communities: An Integrative Review.

BACKGROUND: American Indian elders have one of the lowest life expectancies in the United States. Disproportionate disease burden, socioeconomic disparities, and higher rates of violence across the lifespan are thought to contribute to higher rates of elder abuse. Elder abuse and higher rates of trauma exposure are linked with adverse outcomes. METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines informed the methodology and assessment of the literature on elder abuse among American Indians. RESULTS: Of the nine studies published in the last 30 years, rates of elder abuse varied by study, location, and tribal affiliation from 4.3% to 45.9%. Large studies with comparison populations found higher rates for American Indians. There was a consensus for three risk factors: substance abuse, mental health problems, and caregiving issues. Importance of tribal norms, the notion of respect conferred to elders, and the concept of acculturation were major culturally relevant themes. Perceived tribal norms and strengths, for example, respect for elders, were at odds with abuse experiences, particularly financial exploitation and neglect. Historical trauma, shame, and fear impacted reporting. There was little consistency in study designs, most were qualitative or mixed methods, samples were small, there was no common measurement tool or time frame for abuse, and there was only one intervention study. IMPLICATIONS: High rates of abuse suggest healthcare providers should be encouraged to screen and intervene despite the lack of empirical evidence. Providers should not assume that traditional culturally ascribed strengths, such as honor and respect for elders, provide any degree of protection against elder abuse.

Review of enhanced recovery programs in benign gynecologic surgery.

INTRODUCTION AND HYPOTHESIS: Enhanced recovery programs (ERPs) are evidence-based protocols designed to improve functional rehabilitation after surgery. ERPs have gained widespread acceptance in many surgical disciplines, and their use leads to significant improvements in patient outcomes while reducing hospital length of stay (LOS). There remains a paucity of data on the use of ERPs in benign gynecologic surgery. The purpose of this review was to evaluate current literature on the use of ERP concepts in benign gynecologic surgery. METHODS: A systematic search of PubMed, CINAHL, Web of Science, and the Cochrane databases was conducted, cross-referencing search terms related to gynecologic surgery and ERP concepts. The search was limited to publications available in English. Studies published prior to 2000, and those involving gynecologic oncology, nonadult patients, and outpatient surgery were excluded. RESULTS: Nine studies were included in the analysis. Due to heterogeneity of the included studies, no statistical pooling was possible and comparison between studies was limited to their respective themes. Primary study outcomes included LOS, postoperative nausea and vomiting (PONV), pain management, patient satisfaction, and hospital costs. Five studies investigated ERPs, two evaluated measures to improve PONV, and four focused on unique aspects of pain management. Across the studies, ERPs that focused on the patients' basic symptoms and recovery were found to have equal, if not better, outcomes than standard practice. CONCLUSIONS: This integrative review supports the implementation of ERPs in benign gynecologic surgery. The results showed that the use of ERPs decreased LOS, improved pain scores, and reduced hospital costs, without increasing perioperative complications. We suggest additional randomized controlled trials of ERP concepts in benign gynecologic surgery to support their more widespread use and application.

How Narrative Focus and a Statistical Map Shape Health Policy Support Among State Legislators.

This study attempts to advance theorizing about health policy advocacy with combinations of narrative focus and a statistical map in an attempt to increase state legislators' support for policies to address the issue of obesity by reducing food deserts. Specifically, we examine state legislators' responses to variations in narrative focus (individual vs. community) about causes and solutions for food deserts in U.S. communities, and a statistical map (presence vs. absence) depicting the prevalence of food deserts across the United States. Using a Web-based randomized experiment (N=496), we show that narrative focus and the statistical map interact to produce different patterns of cognitive response and support for policies to reduce the prevalence of food deserts. The presence of a statistical map showing the prevalence of food deserts in the United States appeared to matter only when combined with an individual narrative, offsetting the fact that the individual narrative in isolation produced fewer thoughts consistent with the story's persuasive goal and more counterarguments in opposition to environmental causes and solutions for obesity than other message conditions. The image did not have an impact when combined with a story describing a community at large. Cognitive responses fully mediated message effects on intended persuasive outcomes. We conclude by discussing the study's contributions to communication theory and practice.